Large fetal sacrococcygeal teratomas

Could early delivery improve outcome?

Cynthia J. Holcroft, Karin J. Blakemore, Edith D. Gurewitsch, Rita W. Driggers, Frances J. Northington, Anne C. Fischer

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Objective: To determine if gestational age (GA) at delivery or tumor size impacts outcome in neonates with very large sacrococcygeal teratomas (SCTs). Methods: Retrospective chart review from 1990 to 2006 of live-born infants with very large SCTs, defined as diameters exceeding 10 cm. Data analyzed using the independent t test and Fisher's exact test, with p values <0.05 considered significant. Results: Nine infants with very large SCTs were identified. Six of the 9 infants survived, 4 of whom had evidence of early hydrops. Mean GA of survivors was 32.2 ± 3.7 versus 31.7 ± 0.6 weeks in nonsurvivors (p = 0.85). Infants with the largest SCTs did not survive. Conclusion: Risks of preterm delivery must be weighed against complications from further enlargement of very large SCTs and against the risks of in utero intervention.

Original languageEnglish (US)
Pages (from-to)55-60
Number of pages6
JournalFetal Diagnosis and Therapy
Volume24
Issue number1
DOIs
StatePublished - Jul 2008

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Teratoma
Gestational Age
Edema
Newborn Infant
Neoplasms

Keywords

  • Prematurity
  • Sacrococcygeal teratoma
  • Survival

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Pediatrics, Perinatology, and Child Health

Cite this

Holcroft, C. J., Blakemore, K. J., Gurewitsch, E. D., Driggers, R. W., Northington, F. J., & Fischer, A. C. (2008). Large fetal sacrococcygeal teratomas: Could early delivery improve outcome? Fetal Diagnosis and Therapy, 24(1), 55-60. https://doi.org/10.1159/000132408

Large fetal sacrococcygeal teratomas : Could early delivery improve outcome? / Holcroft, Cynthia J.; Blakemore, Karin J.; Gurewitsch, Edith D.; Driggers, Rita W.; Northington, Frances J.; Fischer, Anne C.

In: Fetal Diagnosis and Therapy, Vol. 24, No. 1, 07.2008, p. 55-60.

Research output: Contribution to journalArticle

Holcroft, CJ, Blakemore, KJ, Gurewitsch, ED, Driggers, RW, Northington, FJ & Fischer, AC 2008, 'Large fetal sacrococcygeal teratomas: Could early delivery improve outcome?', Fetal Diagnosis and Therapy, vol. 24, no. 1, pp. 55-60. https://doi.org/10.1159/000132408
Holcroft CJ, Blakemore KJ, Gurewitsch ED, Driggers RW, Northington FJ, Fischer AC. Large fetal sacrococcygeal teratomas: Could early delivery improve outcome? Fetal Diagnosis and Therapy. 2008 Jul;24(1):55-60. https://doi.org/10.1159/000132408
Holcroft, Cynthia J. ; Blakemore, Karin J. ; Gurewitsch, Edith D. ; Driggers, Rita W. ; Northington, Frances J. ; Fischer, Anne C. / Large fetal sacrococcygeal teratomas : Could early delivery improve outcome?. In: Fetal Diagnosis and Therapy. 2008 ; Vol. 24, No. 1. pp. 55-60.
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