TY - JOUR
T1 - Left ventricular mass as determined by magnetic resonance imaging in male endurance athletes
AU - Milliken, Martin C.
AU - Stray-Gundersen, James
AU - Peshock, Ronald M
AU - Katz, Jose
AU - Mitchell, Jere H
N1 - Funding Information:
From the Departments of Internal Medicine and Orthopedic Surgery, and the Harry S. Moss Heart Center, University of Texas Southwestern Medical Center at Dallas, and the St. Paul/U.T. Southwestern Human Performance Center, Dallas, Texas. This study was supported in part by the Lawson and Rogers Lacy Research Fund in Cardiovascular Diseases. Dr. Milliken was an American Heart Association Medical Student Fellow during the completion of this study. Drs. Katz and Pe-shock’s work was supported by Training Grant HL07360 and Clinical Investigator Award HLOl157, respectively, from the NaYional Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland. Manuscript received March 14, 1988; revised manuscript received and accepted March 24, 1988. Address for reprints: Jere H. Mitchell, MD, U.T. Southwestern/ Moss Heart Center, 5323 Harry Hines Boulevard, Dallas, Texas 75235-9034.
PY - 1988/8/1
Y1 - 1988/8/1
N2 - Although many studies of the effect of dynamic exercise training on left ventricular (LV) mass have been reported, controversy continues to exist. Previous work has been criticized because of the techniques used for measuring LV mass, the variable level of training of the subjects recruited and the methods used to normalize the data. In an attempt to resolve this controversy, LV mass was determined using the very accurate and reproducible technique of magnetic resonance imaging (MRI). Highly trained competitive athletes including crosscountry skiers, endurance cyclists and long distance runners (VO2max = 77 ± 1, 72 ± 2 and 75 ± 2 ml (kg × min)-1, respectively) were examined. The data were normalized for body weight, body surface area and lean body mass. LV mass was significantly greater in skiers (239 ± 9 g), runners (244 ± 10 g) and cyclists (258 ± 11 g) when compared with nonathletic control subjects (189 ± 6 g) (p < 0.001), which represents percent differences of 26, 29 and 37%, respectively. LV mass remained greater in the athletes, regardless of the method used to normalize the data. In addition, there was a good correlation between LV mass and VO2max (r = 0.80, p < 0.001). It was concluded that LV mass is significantly greater in highly trained competitive endurance athletes and that normalizing LV mass with respect to body weight, body surface area or lean body mass does not alter this relation.
AB - Although many studies of the effect of dynamic exercise training on left ventricular (LV) mass have been reported, controversy continues to exist. Previous work has been criticized because of the techniques used for measuring LV mass, the variable level of training of the subjects recruited and the methods used to normalize the data. In an attempt to resolve this controversy, LV mass was determined using the very accurate and reproducible technique of magnetic resonance imaging (MRI). Highly trained competitive athletes including crosscountry skiers, endurance cyclists and long distance runners (VO2max = 77 ± 1, 72 ± 2 and 75 ± 2 ml (kg × min)-1, respectively) were examined. The data were normalized for body weight, body surface area and lean body mass. LV mass was significantly greater in skiers (239 ± 9 g), runners (244 ± 10 g) and cyclists (258 ± 11 g) when compared with nonathletic control subjects (189 ± 6 g) (p < 0.001), which represents percent differences of 26, 29 and 37%, respectively. LV mass remained greater in the athletes, regardless of the method used to normalize the data. In addition, there was a good correlation between LV mass and VO2max (r = 0.80, p < 0.001). It was concluded that LV mass is significantly greater in highly trained competitive endurance athletes and that normalizing LV mass with respect to body weight, body surface area or lean body mass does not alter this relation.
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U2 - 10.1016/0002-9149(88)90228-7
DO - 10.1016/0002-9149(88)90228-7
M3 - Article
C2 - 2969673
AN - SCOPUS:0023770873
SN - 0002-9149
VL - 62
SP - 301
EP - 305
JO - The American journal of cardiology
JF - The American journal of cardiology
IS - 4
ER -