Lipoprotein and receptor interactions in vivo

J. Herz, T. E. Willnow

Research output: Contribution to journalReview article

85 Scopus citations

Abstract

A substantial number of animal models aimed at the genetic dissection of lipid metabolism have been generated recently. Transgenic and knockout mice, in which the receptors or apolipoproteins are overexpressed or destroyed, combined with virus-mediated gene transfer in vivo have advanced our understanding of the complex physiological and pathophysiological processes involved in lipid metabolism, including hepatic lipoprotein uptake and the formation of atherosclerotic lesions.

Original languageEnglish (US)
Pages (from-to)97-103
Number of pages7
JournalCurrent Opinion in Lipidology
Volume6
Issue number2
DOIs
StatePublished - Jan 1 1995

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Molecular Biology
  • Genetics
  • Nutrition and Dietetics
  • Cardiology and Cardiovascular Medicine
  • Cell Biology

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