TY - JOUR
T1 - Lipoprotein receptors
T2 - Beacons to neurons?
AU - Herz, Joachim
N1 - Funding Information:
J.H. is an Established Investigator of the American Heart Association and Parke-Davis, and is supported by grants from the NIH, the Alzheimer Association, and the Perot Family Foundation.
PY - 2001/4/1
Y1 - 2001/4/1
N2 - Lipoprotein receptors were originally considered simply as cellular transporters for cholesterol and other lipids. This view is rapidly changing. Signaling functions have recently been recognized in several members of the low-density lipoprotein receptor gene family. These Apolipoprotein E receptors are highly expressed in the developing and in the mature nervous system, in which they regulate crucial developmental processes and might also participate in synaptic neurotransmission.
AB - Lipoprotein receptors were originally considered simply as cellular transporters for cholesterol and other lipids. This view is rapidly changing. Signaling functions have recently been recognized in several members of the low-density lipoprotein receptor gene family. These Apolipoprotein E receptors are highly expressed in the developing and in the mature nervous system, in which they regulate crucial developmental processes and might also participate in synaptic neurotransmission.
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U2 - 10.1016/S0166-2236(00)01768-9
DO - 10.1016/S0166-2236(00)01768-9
M3 - Review article
C2 - 11249989
AN - SCOPUS:0035313889
SN - 0166-2236
VL - 24
SP - 193
EP - 195
JO - Trends in Neurosciences
JF - Trends in Neurosciences
IS - 4
ER -