Liver transplantation in HIV patients

Alyson N. Fox, Parsia A. Vagefi, Peter G. Stock

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

In the last three decades, the management of human immunodeficiency virus (HIV) has improved dramatically. The use of combination antiretroviral therapy (ART) has been successful at preventing death and the myriad infectious, malignant, and immune-mediated complications of HIV. Once considered to be a fatal disease, HIV is now considered by many to be a chronic disease; those affected may now live to experience complications of other coexistent diseases. Liver disease has been increasingly recognized as a leading cause of non-HIV/acquired immunodeficiency syndrome- (AIDS-) related morbidity and mortality in this population.123 Although liver transplantation offers the opportunity to prolong life, the transplant community has been slow to recognize the chronicity of HIV and potential for transplantation within this population. The experience with liver transplantation in HIV-positive patients is evolving and successful outcomes have been observed when specific criteria are used to select candidates.

Original languageEnglish (US)
Pages (from-to)177-185
Number of pages9
JournalSeminars in Liver Disease
Volume32
Issue number2
DOIs
StatePublished - Jul 6 2012
Externally publishedYes

Fingerprint

Liver Transplantation
HIV
Liver Diseases
Chronic Disease
Transplantation
Morbidity
Transplants
Mortality
Population

Keywords

  • HIV
  • liver transplantation
  • viral hepatitis

ASJC Scopus subject areas

  • Hepatology

Cite this

Liver transplantation in HIV patients. / Fox, Alyson N.; Vagefi, Parsia A.; Stock, Peter G.

In: Seminars in Liver Disease, Vol. 32, No. 2, 06.07.2012, p. 177-185.

Research output: Contribution to journalArticle

Fox, Alyson N. ; Vagefi, Parsia A. ; Stock, Peter G. / Liver transplantation in HIV patients. In: Seminars in Liver Disease. 2012 ; Vol. 32, No. 2. pp. 177-185.
@article{2ec118b9960c4dfbb3852d196c234db8,
title = "Liver transplantation in HIV patients",
abstract = "In the last three decades, the management of human immunodeficiency virus (HIV) has improved dramatically. The use of combination antiretroviral therapy (ART) has been successful at preventing death and the myriad infectious, malignant, and immune-mediated complications of HIV. Once considered to be a fatal disease, HIV is now considered by many to be a chronic disease; those affected may now live to experience complications of other coexistent diseases. Liver disease has been increasingly recognized as a leading cause of non-HIV/acquired immunodeficiency syndrome- (AIDS-) related morbidity and mortality in this population.123 Although liver transplantation offers the opportunity to prolong life, the transplant community has been slow to recognize the chronicity of HIV and potential for transplantation within this population. The experience with liver transplantation in HIV-positive patients is evolving and successful outcomes have been observed when specific criteria are used to select candidates.",
keywords = "HIV, liver transplantation, viral hepatitis",
author = "Fox, {Alyson N.} and Vagefi, {Parsia A.} and Stock, {Peter G.}",
year = "2012",
month = "7",
day = "6",
doi = "10.1055/s-0032-1316474",
language = "English (US)",
volume = "32",
pages = "177--185",
journal = "Seminars in Liver Disease",
issn = "0272-8087",
publisher = "Thieme Medical Publishers",
number = "2",

}

TY - JOUR

T1 - Liver transplantation in HIV patients

AU - Fox, Alyson N.

AU - Vagefi, Parsia A.

AU - Stock, Peter G.

PY - 2012/7/6

Y1 - 2012/7/6

N2 - In the last three decades, the management of human immunodeficiency virus (HIV) has improved dramatically. The use of combination antiretroviral therapy (ART) has been successful at preventing death and the myriad infectious, malignant, and immune-mediated complications of HIV. Once considered to be a fatal disease, HIV is now considered by many to be a chronic disease; those affected may now live to experience complications of other coexistent diseases. Liver disease has been increasingly recognized as a leading cause of non-HIV/acquired immunodeficiency syndrome- (AIDS-) related morbidity and mortality in this population.123 Although liver transplantation offers the opportunity to prolong life, the transplant community has been slow to recognize the chronicity of HIV and potential for transplantation within this population. The experience with liver transplantation in HIV-positive patients is evolving and successful outcomes have been observed when specific criteria are used to select candidates.

AB - In the last three decades, the management of human immunodeficiency virus (HIV) has improved dramatically. The use of combination antiretroviral therapy (ART) has been successful at preventing death and the myriad infectious, malignant, and immune-mediated complications of HIV. Once considered to be a fatal disease, HIV is now considered by many to be a chronic disease; those affected may now live to experience complications of other coexistent diseases. Liver disease has been increasingly recognized as a leading cause of non-HIV/acquired immunodeficiency syndrome- (AIDS-) related morbidity and mortality in this population.123 Although liver transplantation offers the opportunity to prolong life, the transplant community has been slow to recognize the chronicity of HIV and potential for transplantation within this population. The experience with liver transplantation in HIV-positive patients is evolving and successful outcomes have been observed when specific criteria are used to select candidates.

KW - HIV

KW - liver transplantation

KW - viral hepatitis

UR - http://www.scopus.com/inward/record.url?scp=84863209231&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863209231&partnerID=8YFLogxK

U2 - 10.1055/s-0032-1316474

DO - 10.1055/s-0032-1316474

M3 - Article

C2 - 22760657

AN - SCOPUS:84863209231

VL - 32

SP - 177

EP - 185

JO - Seminars in Liver Disease

JF - Seminars in Liver Disease

SN - 0272-8087

IS - 2

ER -