Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells

Katrijn Coen, Ronald S. Flannagan, Szilvia Baron, Luciene R. Carraro-Lacroix, Dong Wang, Wendy Vermeire, Christine Michiels, Sebastian Munck, Veerle Baert, Shuzo Sugita, Frank Wuytack, Peter Robin Hiesinger, Sergio Grinstein, Wim Annaert

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Medicine & Life Sciences