Magnetic resonance imaging of pelvic musculoskeletal and genitourinary anatomy in patients before and after complete primary repair of bladder exstrophy

Patricio C. Gargollo, Joseph G. Borer, Alan B. Retik, Craig A Peters, David A. Diamond, Anthony Atala, Carol E. Barnewolt, Joao Pippe-Salle, John P. Gearhart

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Purpose: We characterize pelvic soft tissue and bony anatomy of patients before and after complete primary repair of exstrophy (CPRE). Materials and Methods: We evaluated 15 measurements on pelvic magnetic resonance imaging (MRI) in patients who underwent CPRE without osteotomy at our institution from 1996 to 2004. MRI protocols included axial, sagittal and coronal fast spin echo proton density sequences. Measurements were compared before and after CPRE using a paired t test, and between patients after CPRE, and age and gender matched controls using linear regression adjusting for the matched case-control groups. Patients older than 3 years with continent intervals longer than 3 hours after CPRE were compared to age and gender matched controls using linear regression. Results: A total of 29 MRIs in 18 patients with exstrophy were available for analysis. Median patient age at postoperative MRI was 25 months (range 4 to 36). The configuration of the post-CPRE pelvis was significantly different from that of controls in all parameters measured including wider symphyseal diastasis (34.5 mm vs less than 1 mm) and more obtuse iliac wing (121° vs 98°), puborectalis (94° vs 49°) and ileococcygeus angles (111° vs 98°). The anatomy of continent patients after CPRE was not significantly different from that of controls in most parameters measured. Conclusions: Comparison of the pelvic anatomy in patients before and after CPRE suggests that after CPRE patients have parameters that more closely approximate, but are still significantly different, from those of control patients. Patients with greater than 3-hour continent intervals after CPRE have anatomic parameters most similar to those of age matched controls.

Original languageEnglish (US)
Pages (from-to)1559-1566
Number of pages8
JournalJournal of Urology
Volume174
Issue number4 II
DOIs
StatePublished - Oct 2005

Keywords

  • Anatomy
  • Bladder exstrophy
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Urology

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    Gargollo, P. C., Borer, J. G., Retik, A. B., Peters, C. A., Diamond, D. A., Atala, A., Barnewolt, C. E., Pippe-Salle, J., & Gearhart, J. P. (2005). Magnetic resonance imaging of pelvic musculoskeletal and genitourinary anatomy in patients before and after complete primary repair of bladder exstrophy. Journal of Urology, 174(4 II), 1559-1566. https://doi.org/10.1097/01.ju.0000175997.60933.fe