Major depression and the risk of attempted suicide

Kevin M. Malone; Gretchen L. Haas; John A. Sweeney; J. John Mann

doi:10.1016/0165-0327(95)00015-F

Major depression and the risk of attempted suicide

Kevin M. Malone, Gretchen L. Haas, John A. Sweeney, J. John Mann

Research output: Contribution to journal › Article › peer-review

237 Scopus citations

Abstract

We examined the risk of attempted suicide in 100 inpatients during a major depressive episode. We hypothesized that patients who attempt suicide have a vulnerability for suicidal behavior independent of severity or duration of depression, manifested by suicide attempts early in the course of a depressive episode. The first 3 months after the onset of an MDE and the first 5 years after the lifetime onset of major depressive disorder represented the highest-risk period for attempted suicide, independent of the severity or duration of depression. Familial, genetic, early-life loss experiences and comorbid alcoholism may be causal factors.

Original language	English (US)
Pages (from-to)	173-185
Number of pages	13
Journal	Journal of affective disorders
Volume	34
Issue number	3
DOIs	https://doi.org/10.1016/0165-0327(95)00015-F
State	Published - Jun 8 1995

ASJC Scopus subject areas

Clinical Psychology
Psychiatry and Mental health

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title = "Major depression and the risk of attempted suicide",

abstract = "We examined the risk of attempted suicide in 100 inpatients during a major depressive episode. We hypothesized that patients who attempt suicide have a vulnerability for suicidal behavior independent of severity or duration of depression, manifested by suicide attempts early in the course of a depressive episode. The first 3 months after the onset of an MDE and the first 5 years after the lifetime onset of major depressive disorder represented the highest-risk period for attempted suicide, independent of the severity or duration of depression. Familial, genetic, early-life loss experiences and comorbid alcoholism may be causal factors.",

author = "Malone, {Kevin M.} and Haas, {Gretchen L.} and Sweeney, {John A.} and Mann, {J. John}",

note = "Funding Information: T. Mieczkowskip erformedm uch of the statistical analysesa nd J. Greenhouse,D epartmento f Biostatisticsa t CarnegieM ellon University,P itts-burgh, provide valuable statisticalc onsultation. D. Abbondanza, D. Dolata, T. Kelly, J. Myers and J. Kaufmanna ssistedin gatheringt he clinical data. This work was supportedb y MHCRC for the Study of Suicidal Behavior (MH467451,b y MH48514 and by Fogarty International Fellowship Award (F05 TWO45381t o K.M. Malone.",

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doi = "10.1016/0165-0327(95)00015-F",

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AU - Malone, Kevin M.

AU - Haas, Gretchen L.

AU - Sweeney, John A.

AU - Mann, J. John

N1 - Funding Information: T. Mieczkowskip erformedm uch of the statistical analysesa nd J. Greenhouse,D epartmento f Biostatisticsa t CarnegieM ellon University,P itts-burgh, provide valuable statisticalc onsultation. D. Abbondanza, D. Dolata, T. Kelly, J. Myers and J. Kaufmanna ssistedin gatheringt he clinical data. This work was supportedb y MHCRC for the Study of Suicidal Behavior (MH467451,b y MH48514 and by Fogarty International Fellowship Award (F05 TWO45381t o K.M. Malone.

PY - 1995/6/8

Y1 - 1995/6/8

N2 - We examined the risk of attempted suicide in 100 inpatients during a major depressive episode. We hypothesized that patients who attempt suicide have a vulnerability for suicidal behavior independent of severity or duration of depression, manifested by suicide attempts early in the course of a depressive episode. The first 3 months after the onset of an MDE and the first 5 years after the lifetime onset of major depressive disorder represented the highest-risk period for attempted suicide, independent of the severity or duration of depression. Familial, genetic, early-life loss experiences and comorbid alcoholism may be causal factors.

AB - We examined the risk of attempted suicide in 100 inpatients during a major depressive episode. We hypothesized that patients who attempt suicide have a vulnerability for suicidal behavior independent of severity or duration of depression, manifested by suicide attempts early in the course of a depressive episode. The first 3 months after the onset of an MDE and the first 5 years after the lifetime onset of major depressive disorder represented the highest-risk period for attempted suicide, independent of the severity or duration of depression. Familial, genetic, early-life loss experiences and comorbid alcoholism may be causal factors.

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Major depression and the risk of attempted suicide

Abstract

ASJC Scopus subject areas

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