Majusculoic acid, a brominated cyclopropyl fatty acid from a marine cyanobacterial mat assemblage

John B. MacMillan; Tadeusz F. Molinski

doi:10.1021/np049596k

Majusculoic acid, a brominated cyclopropyl fatty acid from a marine cyanobacterial mat assemblage

John B. MacMillan, Tadeusz F. Molinski

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43 Scopus citations

Abstract

The novel antifungal compound majusculoic acid was isolated from a cyanobacterial mat microbial community. The structure of majusculoic acid was solved by interpretation of mass spectrometric and NMR data and conversion to the corresponding methyl ester. Majusculoic acid exhibits antifungal activity against Candida albicans ATCC 14503 (MIC 8 μM).

Original language	English (US)
Pages (from-to)	604-606
Number of pages	3
Journal	Journal of Natural Products
Volume	68
Issue number	4
DOIs	https://doi.org/10.1021/np049596k
State	Published - Apr 2005

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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10.1021/np049596k

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title = "Majusculoic acid, a brominated cyclopropyl fatty acid from a marine cyanobacterial mat assemblage",

abstract = "The novel antifungal compound majusculoic acid was isolated from a cyanobacterial mat microbial community. The structure of majusculoic acid was solved by interpretation of mass spectrometric and NMR data and conversion to the corresponding methyl ester. Majusculoic acid exhibits antifungal activity against Candida albicans ATCC 14503 (MIC 8 μM).",

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AU - Molinski, Tadeusz F.

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AB - The novel antifungal compound majusculoic acid was isolated from a cyanobacterial mat microbial community. The structure of majusculoic acid was solved by interpretation of mass spectrometric and NMR data and conversion to the corresponding methyl ester. Majusculoic acid exhibits antifungal activity against Candida albicans ATCC 14503 (MIC 8 μM).

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Majusculoic acid, a brominated cyclopropyl fatty acid from a marine cyanobacterial mat assemblage

Abstract

ASJC Scopus subject areas

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