Majusculoic acid, a brominated cyclopropyl fatty acid from a marine cyanobacterial mat assemblage

John B. MacMillan, Tadeusz F. Molinski

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

The novel antifungal compound majusculoic acid was isolated from a cyanobacterial mat microbial community. The structure of majusculoic acid was solved by interpretation of mass spectrometric and NMR data and conversion to the corresponding methyl ester. Majusculoic acid exhibits antifungal activity against Candida albicans ATCC 14503 (MIC 8 μM).

Original languageEnglish (US)
Pages (from-to)604-606
Number of pages3
JournalJournal of Natural Products
Volume68
Issue number4
DOIs
StatePublished - Apr 2005

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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