Malignant granular cell tumor

S. T. Gokaslan; J. A. Terzakis; E. A. Santagada

doi:10.1111/j.1600-0560.1994.tb00271.x

Malignant granular cell tumor

S. T. Gokaslan, J. A. Terzakis, E. A. Santagada

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44 Scopus citations

Abstract

We report a case of malignant granular cell tumor present in the left medial mid‐thigh of a 69‐year‐old black male. The lesion was grossly fungating, partially ulcerated and measured 14 cm in largest diameter. Light microscopy, electron microscopy and immunohistochemistry techniques were used to confirm the preliminary cytologic diagnosis of malignant granular cell tumor. Diagnostic criteria of malignancy for such lesions are reviewed. Immunohistochemical and ultrastructural analyses support a neural or Schwann cell origin for the tumor. Clinical outcome for such lesions is discussed.

Original language	English (US)
Pages (from-to)	263-270
Number of pages	8
Journal	Journal of Cutaneous Pathology
Volume	21
Issue number	3
DOIs	https://doi.org/10.1111/j.1600-0560.1994.tb00271.x
State	Published - Jun 1994

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology
Dermatology

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10.1111/j.1600-0560.1994.tb00271.x

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title = "Malignant granular cell tumor",

abstract = "We report a case of malignant granular cell tumor present in the left medial mid‐thigh of a 69‐year‐old black male. The lesion was grossly fungating, partially ulcerated and measured 14 cm in largest diameter. Light microscopy, electron microscopy and immunohistochemistry techniques were used to confirm the preliminary cytologic diagnosis of malignant granular cell tumor. Diagnostic criteria of malignancy for such lesions are reviewed. Immunohistochemical and ultrastructural analyses support a neural or Schwann cell origin for the tumor. Clinical outcome for such lesions is discussed.",

author = "Gokaslan, {S. T.} and Terzakis, {J. A.} and Santagada, {E. A.}",

year = "1994",

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doi = "10.1111/j.1600-0560.1994.tb00271.x",

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AU - Gokaslan, S. T.

AU - Terzakis, J. A.

AU - Santagada, E. A.

PY - 1994/6

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N2 - We report a case of malignant granular cell tumor present in the left medial mid‐thigh of a 69‐year‐old black male. The lesion was grossly fungating, partially ulcerated and measured 14 cm in largest diameter. Light microscopy, electron microscopy and immunohistochemistry techniques were used to confirm the preliminary cytologic diagnosis of malignant granular cell tumor. Diagnostic criteria of malignancy for such lesions are reviewed. Immunohistochemical and ultrastructural analyses support a neural or Schwann cell origin for the tumor. Clinical outcome for such lesions is discussed.

AB - We report a case of malignant granular cell tumor present in the left medial mid‐thigh of a 69‐year‐old black male. The lesion was grossly fungating, partially ulcerated and measured 14 cm in largest diameter. Light microscopy, electron microscopy and immunohistochemistry techniques were used to confirm the preliminary cytologic diagnosis of malignant granular cell tumor. Diagnostic criteria of malignancy for such lesions are reviewed. Immunohistochemical and ultrastructural analyses support a neural or Schwann cell origin for the tumor. Clinical outcome for such lesions is discussed.

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Malignant granular cell tumor

Abstract

ASJC Scopus subject areas

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