Management of the open abdomen: A systematic review with meta-analysis and practice management guideline from the Eastern Association for the Surgery of Trauma

Eric J. Mahoney, Nikolay Bugaev, Rachel Appelbaum, Anna Goldenberg-Sandau, Gerard A. Baltazar, Joseph Posluszny, Linda Dultz, Susan Kartiko, George Kasotakis, John Como, Eric Klein

Research output: Contribution to journalReview articlepeer-review

Abstract

BACKGROUND Multiple techniques describe the management of the open abdomen (OA) and restoration of abdominal wall integrity after damage-control laparotomy (DCL). It is unclear which operative technique provides the best method of achieving primary myofascial closure at the index hospitalization. METHODS A writing group from the Eastern Association for the Surgery of Trauma performed a systematic review and meta-analysis of the current literature regarding OA management strategies in the adult population after DCL. The group sought to understand if fascial traction techniques or techniques to reduce visceral edema improved the outcomes in these patients. The Grading of Recommendations Assessment, Development and Evaluation methodology was utilized, meta-analyses were performed, and an evidence profile was generated. RESULTS Nineteen studies met inclusion criteria. Overall, the use of fascial traction techniques was associated with improved primary myofascial closure during the index admission (relative risk, 0.32) and fewer hernias (relative risk, 0.11.) The use of fascial traction techniques did not increase the risk of enterocutaneous fistula formation nor mortality. Techniques to reduce visceral edema may improve the rate of closure; however, these studies were very limited and suffered significant heterogeneity. CONCLUSION We conditionally recommend the use of a fascial traction system over routine care when treating a patient with an OA after DCL. This recommendation is based on the benefit of improved primary myofascial closure without worsening mortality or enterocutaneous fistula formation. We are unable to make any recommendations regarding techniques to reduce visceral edema. LEVEL OF EVIDENCE Systematic Review and Meta-Analysis; Level IV.

Original languageEnglish (US)
Pages (from-to)E110-E118
JournalJournal of Trauma and Acute Care Surgery
Volume93
Issue number3
DOIs
StatePublished - Sep 1 2022

Keywords

  • fascial traction
  • Open abdomen
  • practice management guidelines
  • primary myofascial closure
  • visceral edema

ASJC Scopus subject areas

  • Surgery
  • Critical Care and Intensive Care Medicine

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