Mechanisms of allosteric regulation of trypanosoma cruzi S-adenosylmethionine decarboxylase

Medicine & Life Sciences

• Adenosylmethionine Decarboxylase 100%
• Allosteric Regulation 90%
• Putrescine 80%
• Trypanosoma cruzi 73%
• Catalytic Domain 23%
• Binding Sites 20%
• 4-amidinoindan-1-one 2'-amidinohydrazone 17%
• Enzymes 16%
• Polyamines 15%
• bis((3-(aminoiminomethyl)phenyl)methylene)carbonimidic dihydrazide trihydrochloride 10%
• Mutation 7%
• Pentamidine 6%
• Mutagenesis 4%
• Parasites 3%
• Data Analysis 3%
• Ligands 3%
• Growth 2%
• Pharmaceutical Preparations 1%

Chemical Compounds

• Putrescine 78%
• Mutation 22%
• Polyamine 18%
• Antiproliferative 8%
• Cofactor 7%
• Biosynthesis 7%
• Enzyme Activity 7%
• Probe 5%
• Drug 4%
• Ligand 3%