TY - JOUR
T1 - Mechanisms of posttransplant hypertension
AU - Sagalowsky, Arthur I
N1 - Funding Information:
From the Nephrology Research and Training Center, Departments of Medicine and Surgery, University of Alabama in Birmingham, University Station, Birmingham. Supported in part by a grant (5 P50 HL25452) from the Specialized Center of Research for Hypertension, National Institutes of Health and a General Clinical Research Centers Grant (RR-0032!. Address reprint requests to Dr Robert G. Luke, Nephrology Research and Training Center, University of Alabama in Birmingham, University Station, Birmingham, AL 35294. © 1985 by The National Kidney Foundation, Inc. 02 72-63861851020A 79-06$03. 0010
PY - 1989/6
Y1 - 1989/6
N2 - Hypertension is a common problem in renal failure patients both before and after renal transplantation. The stable allograft can maintain salt, volume, and blood pressure homeostasis and is not intrinsically a hypertensive model. The causes of severe posttransplant hypertension are multiple. Renal vascular tone, body salt and volume status, and renin release are all connected and influenced by immunosuppressive medications, allograft function, and native kidney presence and function. The role of each of these in posttransplant hypertension is reviewed. In most cases, severe hypertension in the stable transplant patient without rejection or transplant renal artery stenosis is greatly improved following native bilateral nephrectomy. Transluminal angioplasty is the preferred initial treatment for transplant renal artery stenosis.
AB - Hypertension is a common problem in renal failure patients both before and after renal transplantation. The stable allograft can maintain salt, volume, and blood pressure homeostasis and is not intrinsically a hypertensive model. The causes of severe posttransplant hypertension are multiple. Renal vascular tone, body salt and volume status, and renin release are all connected and influenced by immunosuppressive medications, allograft function, and native kidney presence and function. The role of each of these in posttransplant hypertension is reviewed. In most cases, severe hypertension in the stable transplant patient without rejection or transplant renal artery stenosis is greatly improved following native bilateral nephrectomy. Transluminal angioplasty is the preferred initial treatment for transplant renal artery stenosis.
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U2 - 10.1007/BF01576894
DO - 10.1007/BF01576894
M3 - Article
AN - SCOPUS:0024341595
SN - 0724-4983
VL - 7
SP - 102
EP - 110
JO - World journal of urology
JF - World journal of urology
IS - 2
ER -