Mechanisms underlying spatial representation revealed through studies of hemispatial neglect

Marlene Behrmann, Thea Ghiselli-crippa, John A. Sweeney, Ilaria Di Matteo, Robert Kass

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

The representations that mediate the coding of spatial position were examined by comparing the behavior of patients with left hemispatial neglect with that of nonneurological control subjects. To determine the spatial coordinate system(s) used to define "left" and "right," eye movements were measured for targets that appeared at 5°, 10°, and 15° to the relative left or right defined with respect to the midline of the eyes, head, or midsaggital plane of the trunk. In the baseline condition, in which the various egocentric midlines were all aligned with the environmental midline, patients were disproportionately slower at initiating saccades to left than right targets, retative to the controls. When either the trunk or the head was rotated and the midline aligned with the most peripheral position while the eyes remained aligned with the midline of the environment, the results did not differ from the baseline condition. However, when the eyes were rotated and the midline aligned with the peripheral position, saccadic reaction time (SRT) differed significantly from the baseline, especially when the eyes were rotated to the right. These findings suggest that target position is coded relative to the current position of gaze (oculocentrically) and that this eye-centered coding is modulated by orbital position (eye-in-head signal). The findings dovetail well with results from existing neurophysiological studies and shed further light on the spatial representations mediated by the human parietal cortex.

Original languageEnglish (US)
Pages (from-to)272-290
Number of pages19
JournalJournal of Cognitive Neuroscience
Volume14
Issue number2
DOIs
StatePublished - Feb 15 2002

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Perceptual Disorders
Head
Parietal Lobe
Saccades
Eye Movements
Reaction Time

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience

Cite this

Mechanisms underlying spatial representation revealed through studies of hemispatial neglect. / Behrmann, Marlene; Ghiselli-crippa, Thea; Sweeney, John A.; Di Matteo, Ilaria; Kass, Robert.

In: Journal of Cognitive Neuroscience, Vol. 14, No. 2, 15.02.2002, p. 272-290.

Research output: Contribution to journalArticle

Behrmann, Marlene ; Ghiselli-crippa, Thea ; Sweeney, John A. ; Di Matteo, Ilaria ; Kass, Robert. / Mechanisms underlying spatial representation revealed through studies of hemispatial neglect. In: Journal of Cognitive Neuroscience. 2002 ; Vol. 14, No. 2. pp. 272-290.
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