Abstract
The core apparatus that regulates circadian rhythm has been extensively studied over the past five years. A looming question remains, however, regarding how this apparatus is adjusted to maintain coordination between physiology and the changing environment. The diversity of stimuli and input pathways that gain access to the circadian clock are summarized. Cellular metabolic states could serve to link physiologic perception of the environment to the circadian oscillatory apparatus. A simple model, integrating biochemical, cellular, and physiologic data, is presented to account for the connection of cellular metabolism and circadian rhythm.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 307-331 |
| Number of pages | 25 |
| Journal | Annual review of biochemistry |
| Volume | 71 |
| DOIs | |
| State | Published - Aug 1 2002 |
Keywords
- Central circadian oscillator
- Circadian rhythm
- Entrainment
- Neural activity
- Restricted feeding
- Suprachiasmatic nucleus
ASJC Scopus subject areas
- Biochemistry
Fingerprint Dive into the research topics of 'Metabolism and the control of circadian rhythms'. Together they form a unique fingerprint.
Cite this
Rutter, J., Reick, M., & McKnight, S. L. (2002). Metabolism and the control of circadian rhythms. Annual review of biochemistry, 71, 307-331. https://doi.org/10.1146/annurev.biochem.71.090501.142857