TY - JOUR
T1 - Milestone clinical trials of the National Surgical Adjuvant Breast and Bowel Project (NSABP)
AU - Rastogi, Priya
AU - Wickerham, D. Lawrence
AU - Geyer, Charles E.
AU - Mamounas, Eleftherios P.
AU - Julian, Thomas B.
AU - Wolmark, Norman
N1 - Publisher Copyright:
© Chinese Clinical Oncology. All rights reserved.
PY - 2017
Y1 - 2017
N2 - The National Surgical Adjuvant Breast and Bowel Project (NSABP) has made significant contributions in reducing the extent of breast surgery and in improving outcomes of patients with early-stage breast cancer through the conduct of large randomized clinical trials evaluating local and systemic therapy. In 2014, the NSABP merged with two other US National Cancer Institute-funded cooperative groups, the Radiation Therapy Oncology Group (RTOG) and the Gynecologic Oncology Group (GOG), to form NRG Oncology. The combined organization has 218 member institutions with more than 600 affiliate centers located throughout the United States, Canada, Puerto Rico, and other international sites. Over the past half century, the NSABP has entered more than 150,000 women into clinical trials of breast cancer treatment and breast cancer prevention. Many of these trials have been instrumental in establishing new standards of care for patients with breast cancer.
AB - The National Surgical Adjuvant Breast and Bowel Project (NSABP) has made significant contributions in reducing the extent of breast surgery and in improving outcomes of patients with early-stage breast cancer through the conduct of large randomized clinical trials evaluating local and systemic therapy. In 2014, the NSABP merged with two other US National Cancer Institute-funded cooperative groups, the Radiation Therapy Oncology Group (RTOG) and the Gynecologic Oncology Group (GOG), to form NRG Oncology. The combined organization has 218 member institutions with more than 600 affiliate centers located throughout the United States, Canada, Puerto Rico, and other international sites. Over the past half century, the NSABP has entered more than 150,000 women into clinical trials of breast cancer treatment and breast cancer prevention. Many of these trials have been instrumental in establishing new standards of care for patients with breast cancer.
KW - Breast cancer
KW - Clinical trials
KW - Locoregional therapy for breast cancer
KW - Systemic therapy for breast cancer
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U2 - 10.21037/cco.2017.02.02
DO - 10.21037/cco.2017.02.02
M3 - Review article
C2 - 28285537
AN - SCOPUS:85013393599
SN - 2304-3865
VL - 6
JO - Chinese Clinical Oncology
JF - Chinese Clinical Oncology
IS - 1
M1 - 7
ER -