Modeling of magnetic bandages for drug targeting: Button vs. Halbach arrays

Urs O. Häfeli, Kelly Gilmour, Amy Zhou, Stanley Lee, Michael E. Hayden

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

Abstract

Magnetic targeting of drugs to diseased tissues, such as non-healing wounds or skin tumors, is a promising clinical use of magnetic microspheres. For successful magnetic targeting, a magnet must be placed in close proximity to the target tissue. In this work the forces exerted on magnetic microspheres by different arrangements of magnets including a simple square magnet, a number of button magnet arrays, and a Halbach array were simulated and compared. Magnetic bandages utilizing a Halbach array configuration were found to yield the best trapping characteristics (large and uniform force distributions) for magnetic targeting applications close to a surface.

Original languageEnglish (US)
Pages (from-to)323-329
Number of pages7
JournalJournal of Magnetism and Magnetic Materials
Volume311
Issue number1 SPEC. ISS.
DOIs
StatePublished - Apr 2007
Externally publishedYes

Keywords

  • Halbach array
  • Magnetic bandage
  • Magnetic drug targeting
  • Magnetic microspheres
  • Modeling
  • Skin ulcer

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

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