Morpholino antisense oligonucleotides: Tools for investigating vertebrate development

Research output: Contribution to journalArticle

105 Citations (Scopus)

Abstract

Antisense oligonucleotides provide a promising approach to investigating gene function in vivo, but their ability to offer unambiguous insights into phenotypes has been debated. The recent use of morpholino antisense oligonucleotides in zebrafish embryos may prove a major advance, but rigorous controls are essential.

Original languageEnglish (US)
Article number1015
JournalGenome Biology
Volume2
Issue number5
StatePublished - 2001

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Morpholinos
Antisense Oligonucleotides
oligonucleotides
Vertebrates
phenotype
embryo
vertebrate
vertebrates
gene
Zebrafish
Danio rerio
embryo (animal)
Embryonic Structures
Phenotype
Genes
genes

ASJC Scopus subject areas

  • Genetics
  • Cell Biology
  • Ecology, Evolution, Behavior and Systematics

Cite this

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title = "Morpholino antisense oligonucleotides: Tools for investigating vertebrate development",
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