Mortality resulting from congenital heart disease among children and adults in the United States, 1999 to 2006

Suzanne M. Gilboa, Jason L. Salemi, Wendy N. Nembhard, David E Fixler, Adolfo Correa

Research output: Contribution to journalArticle

239 Citations (Scopus)

Abstract

Background-: Previous reports suggest that mortality resulting from congenital heart disease (CHD) among infants and young children has been decreasing. There is little population-based information on CHD mortality trends and patterns among older children and adults. Methods and results-: We used data from death certificates filed in the United States from 1999 to 2006 to calculate annual CHD mortality by age at death, race-ethnicity, and sex. To calculate mortality rates for individuals â‰1 1 year of age, population counts from the US Census were used in the denominator; for infant mortality, live birth counts were used. From 1999 to 2006, there were 41 494 CHD-related deaths and 27 960 deaths resulting from CHD (age-standardized mortality rates, 1.78 and 1.20 per 100 000, respectively). During this period, mortality resulting from CHD declined 24.1% overall. Mortality resulting from CHD significantly declined among all race-ethnicities studied. However, disparities persisted; overall and among infants, mortality resulting from CHD was consistently higher among non-Hispanic blacks compared with non-Hispanic whites. Infant mortality accounted for 48.1% of all mortality resulting from CHD; among those who survived the first year of life, 76.1% of deaths occurred during adulthood (≥18 years of age). Conclusions-: CHD mortality continued to decline among both children and adults; however, differences between race-ethnicities persisted. A large proportion of CHD-related mortality occurred during infancy, although significant CHD mortality occurred during adulthood, indicating the need for adult CHD specialty management.

Original languageEnglish (US)
Pages (from-to)2254-2263
Number of pages10
JournalCirculation
Volume122
Issue number22
DOIs
StatePublished - Nov 30 2010

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Heart Diseases
Mortality
Infant Mortality
Death Certificates
Live Birth
Censuses
Disease Management
Population

Keywords

  • epidemiology
  • heart defects, congenital
  • mortality
  • race
  • vital statistics

ASJC Scopus subject areas

  • Physiology (medical)
  • Cardiology and Cardiovascular Medicine

Cite this

Mortality resulting from congenital heart disease among children and adults in the United States, 1999 to 2006. / Gilboa, Suzanne M.; Salemi, Jason L.; Nembhard, Wendy N.; Fixler, David E; Correa, Adolfo.

In: Circulation, Vol. 122, No. 22, 30.11.2010, p. 2254-2263.

Research output: Contribution to journalArticle

Gilboa, Suzanne M. ; Salemi, Jason L. ; Nembhard, Wendy N. ; Fixler, David E ; Correa, Adolfo. / Mortality resulting from congenital heart disease among children and adults in the United States, 1999 to 2006. In: Circulation. 2010 ; Vol. 122, No. 22. pp. 2254-2263.
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