Mouse fibroblasts A9 are deficient in HPRT and APRT

R. P. Cox, M. R. Krauss, M. E. Balis, J. Dancis

Research output: Contribution to journalArticle

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Abstract

The A9 cell line, frequently used for cell hybridization, is deficient in both HPRT and APRT. Evidently the parent L cell line from which A9 was derived had previously undergone a spontaneous mutation to APRT deficiency. The double enzyme deficiency in A9 cells should be recognized by investigators who use this line for studies on somatic cell genetics.

Original languageEnglish (US)
Pages (from-to)272-273
Number of pages2
JournalAmerican Journal of Human Genetics
Volume26
Issue number2
StatePublished - 1974

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Hypoxanthine Phosphoribosyltransferase
Fibroblasts
Cell Line
Research Personnel
Mutation
Enzymes

ASJC Scopus subject areas

  • Genetics

Cite this

Cox, R. P., Krauss, M. R., Balis, M. E., & Dancis, J. (1974). Mouse fibroblasts A9 are deficient in HPRT and APRT. American Journal of Human Genetics, 26(2), 272-273.

Mouse fibroblasts A9 are deficient in HPRT and APRT. / Cox, R. P.; Krauss, M. R.; Balis, M. E.; Dancis, J.

In: American Journal of Human Genetics, Vol. 26, No. 2, 1974, p. 272-273.

Research output: Contribution to journalArticle

Cox, RP, Krauss, MR, Balis, ME & Dancis, J 1974, 'Mouse fibroblasts A9 are deficient in HPRT and APRT', American Journal of Human Genetics, vol. 26, no. 2, pp. 272-273.
Cox, R. P. ; Krauss, M. R. ; Balis, M. E. ; Dancis, J. / Mouse fibroblasts A9 are deficient in HPRT and APRT. In: American Journal of Human Genetics. 1974 ; Vol. 26, No. 2. pp. 272-273.
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