MRI vs. histologic measurement of breast cancer following chemotherapy: Comparison with x-ray mammography and palpation

P. T. Weatherall; Gregory F. Evans; Gregory J. Metzger; M. Hossein Saborrian; A. Marilyn Leitch

doi:10.1002/jmri.1124

MRI vs. histologic measurement of breast cancer following chemotherapy: Comparison with x-ray mammography and palpation

P. T. Weatherall, Gregory F. Evans, Gregory J. Metzger, M. Hossein Saborrian, A. Marilyn Leitch

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152 Scopus citations

Abstract

Twenty consecutive patients with breast cancer were evaluated following chemotherapy using MRI to assess the size of cancer residua and compare these data with subsequent histologic measurements of the viable tumor. This retrospective study also involved assessment of the preoperative size of the malignancy as determined by physical exam and x-ray mammogram. These values were later compared with the histology. The tumor size correlation coefficient between MRI and pathologic analysis was the highest, at 0.93. Physical exam and x-ray mammography (available for 17 patients) produced correlation coefficients of 0.72 and 0.63, respectively, compared to histologic measurement. The accuracy of MRI did not vary with the size of cancer residua. MRI is an accurate method for preoperative assessment of breast cancer residua following chemotherapy.

Original language	English (US)
Pages (from-to)	868-875
Number of pages	8
Journal	Journal of Magnetic Resonance Imaging
Volume	13
Issue number	6
DOIs	https://doi.org/10.1002/jmri.1124
State	Published - Jun 2001

Keywords

Breast neoplasms
Comparative studies
MR
Malignant neoplasm
Staging

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1002/jmri.1124

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abstract = "Twenty consecutive patients with breast cancer were evaluated following chemotherapy using MRI to assess the size of cancer residua and compare these data with subsequent histologic measurements of the viable tumor. This retrospective study also involved assessment of the preoperative size of the malignancy as determined by physical exam and x-ray mammogram. These values were later compared with the histology. The tumor size correlation coefficient between MRI and pathologic analysis was the highest, at 0.93. Physical exam and x-ray mammography (available for 17 patients) produced correlation coefficients of 0.72 and 0.63, respectively, compared to histologic measurement. The accuracy of MRI did not vary with the size of cancer residua. MRI is an accurate method for preoperative assessment of breast cancer residua following chemotherapy.",

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AU - Weatherall, P. T.

AU - Evans, Gregory F.

AU - Metzger, Gregory J.

AU - Saborrian, M. Hossein

AU - Leitch, A. Marilyn

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MRI vs. histologic measurement of breast cancer following chemotherapy: Comparison with x-ray mammography and palpation

Abstract

Keywords

ASJC Scopus subject areas

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