Mucinous cystadenocarcinoma of the testis

A case report

Alina Cornelia Iuga, Jason Mull, Rashmi Batra, William Miller

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We present a rare case of unilateral intratesticular cystadenocarcinoma with mucinous differentiation in a 71-year-old male patient. The orchiectomy specimen revealed a 3.5-cm well to moderately differentiated cystic neoplasm with elongated fine papillary structures lined by columnar epithelium with alternating goblet and ciliated cells completely replacing the testicular parenchyma. Immunohistochemical studies showed positivity for cytokeratin 20, carcinoembryonic antigen, and mucin 2, and negativity for cytokeratin 7, mucin 5AC, vimentin, thyroid transcription factor 1, Wilms' tumor 1, and cancer antigen 125. The current case shows a focal cyst-lining component with benign appearance. Imaging studies and colonoscopy showed no evidence of other suspicious lesions. This tumor resembles morphologically to an intestinal-type ovarian surface epithelial tumor.

Original languageEnglish (US)
Pages (from-to)1343-1347
Number of pages5
JournalHuman Pathology
Volume42
Issue number9
DOIs
StatePublished - Sep 2011

Fingerprint

Mucinous Cystadenocarcinoma
Testis
Mucin 5AC
Neoplasms
Mucin-2
Keratin-20
Keratin-7
Goblet Cells
Orchiectomy
Wilms Tumor
Carcinoembryonic Antigen
Vimentin
Colonoscopy
Cysts
Epithelium
Antigens

Keywords

  • Cyst
  • Cystadenocarcinoma
  • Intestinal
  • Intratesticular
  • Mucinous
  • Ovarian surface epithelial tumor
  • Testicular adenocarcinoma
  • Testis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Mucinous cystadenocarcinoma of the testis : A case report. / Iuga, Alina Cornelia; Mull, Jason; Batra, Rashmi; Miller, William.

In: Human Pathology, Vol. 42, No. 9, 09.2011, p. 1343-1347.

Research output: Contribution to journalArticle

Iuga, Alina Cornelia ; Mull, Jason ; Batra, Rashmi ; Miller, William. / Mucinous cystadenocarcinoma of the testis : A case report. In: Human Pathology. 2011 ; Vol. 42, No. 9. pp. 1343-1347.
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