Multifocal motor sensory demyelinating neuropathy: Inflammatory demyelinating polyradiculoneuropathy

S. J. Oh, C. LaGanke, R. Powers, G. I. Wolfe, R. A. Quinton, D. K. Burns

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

The authors present two cases that provide the first autopsy findings in multifocal acquired demyelinating sensory and motor neuropathy (MADSAMN). Both cases documented multifocal but asymmetric demyelinating neuropathy with rare axonal degeneration. One case clearly documented an inflammatory polyradiculoplexoneuropathy, confirming the inflammatory nature of this neuropathy. This study showed that MADSAMN is an inflammatory demyelinating polyradiculoneuropathy that shares histologic features observed in chronic inflammatory demyelinating polyradiculoneuropathy and multifocal motor neuropathy (MMN), suggesting a similar immunopathogenesis for these entities.

Original languageEnglish (US)
Pages (from-to)1639-1642
Number of pages4
JournalNeurology
Volume65
Issue number10
DOIs
StatePublished - Nov 2005

ASJC Scopus subject areas

  • Clinical Neurology

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