Myeloma tumor satellite DNA: A role in ribosomal RNA synthesis

Leonard J. Greenberg, Jonathan W. Uhr

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

The data in the present study is consistent with the concept of duplicated adjacent stretches of DNA coding for 16 and 28 S ribosomal RNA. The four-fold increase in hybrid formation between 16 S RNA and satellite DNA strongly suggests that satellite DNA codes for this RNA. The capacity for both DNA's to form hybrids with respect to 28 S RNA could mean that the DNA stretches coding for 28 S RNA are adjacent to those coding for 16 S RNA but are of slightly higher buoyant density. 10 S RNA appears to be coded for by the major band DNA only.

Original languageEnglish (US)
Pages (from-to)523-528
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume27
Issue number5
DOIs
StatePublished - Jun 9 1967

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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