Myokymia, neuromyotonia, dermatomyositis, and voltage-gated K+ channel antibodies

Shin J. Oh, Anjaneyulu Alapati, Gwen C. Claussen, Steven Vernino

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

A young woman presented with facial myokymia in association with dermatomyositis. There was no evidence of peripheral neuropathy. Needle electromyography showed prominent myokymic discharges and brief neuromyotonic discharges in addition to many small-amplitude, shortduration motor unit potentials. Myokymia and dermatomyositis both responded to immunosuppressive treatment. The presence of antibodies to voltage-gated potassium channels and the association with dermatomyositis indicated an autoimmune cause for myokymia, which may have been due to reversible peripheral nerve hyperexcitability.

Original languageEnglish (US)
Pages (from-to)757-760
Number of pages4
JournalMuscle and Nerve
Volume27
Issue number6
DOIs
StatePublished - Jun 1 2003

Keywords

  • Dermatomyositis
  • Isaacs' syndrome
  • Myokymia
  • Neuromyotonia
  • Voltage-gated K channel antibody

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)

Fingerprint Dive into the research topics of 'Myokymia, neuromyotonia, dermatomyositis, and voltage-gated K<sup>+</sup> channel antibodies'. Together they form a unique fingerprint.

  • Cite this