Nanostructured luminescently labeled nucleic acids

Larry J. Kricka, Paolo Fortina, Jason Y. Park

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

Important and emerging trends at the interface of luminescence, nucleic acids and nanotechnology are: (i) the conventional luminescence labeling of nucleic acid nanostructures (e.g. DNA tetrahedron); (ii) the labeling of bulk nucleic acids (e.g. single-stranded DNA, double-stranded DNA) with nanostructured luminescent labels (e.g. copper nanoclusters); and (iii) the labeling of nucleic acid nanostructures (e.g. origami DNA) with nanostructured luminescent labels (e.g. silver nanoclusters). This review surveys recent advances in these three different approaches to the generation of nanostructured luminescently labeled nucleic acids, and includes both direct and indirect labeling methods.

Original languageEnglish (US)
Pages (from-to)132-141
Number of pages10
JournalLuminescence
Volume32
Issue number2
DOIs
StatePublished - Mar 1 2017

Keywords

  • chemiluminescence
  • electrochemiluminescence
  • nanostructures
  • nucleic acid labeling
  • photoluminescence

ASJC Scopus subject areas

  • Biophysics
  • Chemistry (miscellaneous)

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