Nanotechnology in Radiation Oncology

Bo Sun, C. Tilden Hagan, Joseph Caster, Andrew Z. Wang

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

Nanotechnology has made remarkable contributions to clinical oncology. Nanotherapeutics and diagnostic tools have distinctive characteristics which allow them superior abilities to deliver therapeutics and imaging agents for radiation oncology. Compared to solid biopsies and imaging, the analysis of circulating tumor cells (CTCs) offers a more rapid, real-time, and less invasive method to monitor the dynamic molecular profiles of tumors. The potential of CTCs to be translated as a novel cancer biomarker has been demonstrated in numerous clinical studies. This review will discuss clinical applications of nanomaterials in radiation oncology and the implication of CTCs in cancer detection and monitoring.

Original languageEnglish (US)
Pages (from-to)1071-1093
Number of pages23
JournalHematology/Oncology Clinics of North America
Volume33
Issue number6
DOIs
StatePublished - Dec 2019
Externally publishedYes

Keywords

  • Cancer biomarkers
  • Circulating tumor DNA
  • Circulating tumor cells
  • Liquid biopsy
  • Nanoparticles
  • Radiosensitization
  • Radiotherapy
  • Tumor imaging

ASJC Scopus subject areas

  • Hematology
  • Oncology

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