Abstract
Since the discovery that actin and actin-related proteins (ARPs) reside in the nucleus as integral subunits of chromatin-modifying and chromatin-remodeling complexes, efforts to uncover their roles in chromatin regulation have met with limited success. In a new study, the previously mysterious helicase-SANT- associated (HSA) domain found in many chromatin regulatory complexes is shown to act as a module that directs recruitment and contributes to the action of actin and ARPs in chromatin regulation.
Original language | English (US) |
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Pages (from-to) | 432-433 |
Number of pages | 2 |
Journal | Nature Structural and Molecular Biology |
Volume | 15 |
Issue number | 5 |
DOIs | |
State | Published - May 2008 |
Externally published | Yes |
ASJC Scopus subject areas
- Structural Biology
- Molecular Biology