New clues to actin function in chromatin regulation

Aaron J. Gottschalk; Ronald C. Conaway; Joan Weliky Conaway

doi:10.1038/nsmb0508-432

New clues to actin function in chromatin regulation

Aaron J. Gottschalk, Ronald C. Conaway, Joan Weliky Conaway

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

Since the discovery that actin and actin-related proteins (ARPs) reside in the nucleus as integral subunits of chromatin-modifying and chromatin-remodeling complexes, efforts to uncover their roles in chromatin regulation have met with limited success. In a new study, the previously mysterious helicase-SANT- associated (HSA) domain found in many chromatin regulatory complexes is shown to act as a module that directs recruitment and contributes to the action of actin and ARPs in chromatin regulation.

Original language	English (US)
Pages (from-to)	432-433
Number of pages	2
Journal	Nature Structural and Molecular Biology
Volume	15
Issue number	5
DOIs	https://doi.org/10.1038/nsmb0508-432
State	Published - May 2008
Externally published	Yes

ASJC Scopus subject areas

Structural Biology
Molecular Biology

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10.1038/nsmb0508-432

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title = "New clues to actin function in chromatin regulation",

abstract = "Since the discovery that actin and actin-related proteins (ARPs) reside in the nucleus as integral subunits of chromatin-modifying and chromatin-remodeling complexes, efforts to uncover their roles in chromatin regulation have met with limited success. In a new study, the previously mysterious helicase-SANT- associated (HSA) domain found in many chromatin regulatory complexes is shown to act as a module that directs recruitment and contributes to the action of actin and ARPs in chromatin regulation.",

author = "Gottschalk, {Aaron J.} and Conaway, {Ronald C.} and Conaway, {Joan Weliky}",

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AU - Conaway, Ronald C.

AU - Conaway, Joan Weliky

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AB - Since the discovery that actin and actin-related proteins (ARPs) reside in the nucleus as integral subunits of chromatin-modifying and chromatin-remodeling complexes, efforts to uncover their roles in chromatin regulation have met with limited success. In a new study, the previously mysterious helicase-SANT- associated (HSA) domain found in many chromatin regulatory complexes is shown to act as a module that directs recruitment and contributes to the action of actin and ARPs in chromatin regulation.

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JF - Nature Structural Biology

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New clues to actin function in chromatin regulation

Abstract

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