TY - JOUR
T1 - New clues to actin function in chromatin regulation
AU - Gottschalk, Aaron J.
AU - Conaway, Ronald C.
AU - Conaway, Joan Weliky
PY - 2008/5
Y1 - 2008/5
N2 - Since the discovery that actin and actin-related proteins (ARPs) reside in the nucleus as integral subunits of chromatin-modifying and chromatin-remodeling complexes, efforts to uncover their roles in chromatin regulation have met with limited success. In a new study, the previously mysterious helicase-SANT- associated (HSA) domain found in many chromatin regulatory complexes is shown to act as a module that directs recruitment and contributes to the action of actin and ARPs in chromatin regulation.
AB - Since the discovery that actin and actin-related proteins (ARPs) reside in the nucleus as integral subunits of chromatin-modifying and chromatin-remodeling complexes, efforts to uncover their roles in chromatin regulation have met with limited success. In a new study, the previously mysterious helicase-SANT- associated (HSA) domain found in many chromatin regulatory complexes is shown to act as a module that directs recruitment and contributes to the action of actin and ARPs in chromatin regulation.
UR - http://www.scopus.com/inward/record.url?scp=43249085297&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=43249085297&partnerID=8YFLogxK
U2 - 10.1038/nsmb0508-432
DO - 10.1038/nsmb0508-432
M3 - Short survey
C2 - 18461045
AN - SCOPUS:43249085297
SN - 1545-9993
VL - 15
SP - 432
EP - 433
JO - Nature Structural and Molecular Biology
JF - Nature Structural and Molecular Biology
IS - 5
ER -