New horizons in the pharmacologic approach to hyponatremia: The V 2 receptor antagonists

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

This article provides an overview of the developing niche for vasopressin 2 receptor antagonists ("vaptans") in the management of hyponatremia in clinical practice. Specific areas of focus include the physiological and clinical rationale for use of this class of medications (including advantages over older and less specific therapeutic modalities), the practical limitations to the use of these new drugs (including issues of tolerability, toxicity, risk, and cost), and the unanswered question of the extent to which correcting hyponatremia will improve clinical outcomes.

Original languageEnglish (US)
JournalJournal of Hospital Medicine
Volume5
Issue numberSUPPL. 3
DOIs
StatePublished - Jul 2010

Fingerprint

Hyponatremia
Costs and Cost Analysis
Pharmaceutical Preparations
Therapeutics
Antidiuretic Hormone Receptor Antagonists

Keywords

  • Arginine vasopressin
  • AVP receptor antagonists
  • Conivaptan
  • Hyponatremia
  • Tolvaptan

ASJC Scopus subject areas

  • Health Policy
  • Assessment and Diagnosis
  • Care Planning
  • Fundamentals and skills
  • Leadership and Management

Cite this

New horizons in the pharmacologic approach to hyponatremia : The V 2 receptor antagonists. / Palmer, Biff F.

In: Journal of Hospital Medicine, Vol. 5, No. SUPPL. 3, 07.2010.

Research output: Contribution to journalArticle

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