New paradigm for lymphocyte granule-mediated cytotoxicity: Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis

Christopher J. Froelich, Kim Orth, Jane Turbov, Prem Seth, Roberta Gottlieb, Bernard Babior, Girish M. Shah, R. Christopher Bleackley, Vishva M. Dixit, William Hanna

Research output: Contribution to journalArticlepeer-review

318 Scopus citations

Fingerprint

Dive into the research topics of 'New paradigm for lymphocyte granule-mediated cytotoxicity: Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis'. Together they form a unique fingerprint.

Medicine & Life Sciences

Chemical Compounds