Nodular regenerative hyperplasia of the liver in a case of myelofibrosis with extramedullary hematopoiesis and secondary portal venous hypertension

J. Shorey, M. N. Weinberg, E. P. Frenkel, B. D. Fallis

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Nodular regenerative hyperplasia of the liver was identified at autopsy in a patient with myelofibrosis with extramedullary hematopoiesis, an association not previously reported. Portal venous hypertension, documented during the patient's terminal hospitalization, was ascribed, in part, to a high rate of blood flow through the enlarged spleen. Possible mechanisms accounting for the development of nodular regenerative hyperplasia of the liver, and evidence provided by this case pertinent to these mechanisms, are discussed.

Original languageEnglish (US)
Pages (from-to)122-125
Number of pages4
JournalAmerican Journal of Clinical Pathology
Volume72
Issue number1
StatePublished - 1979

Fingerprint

Extramedullary Hematopoiesis
Primary Myelofibrosis
Portal Hypertension
Hyperplasia
Liver
Splenomegaly
Autopsy
Hospitalization

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Nodular regenerative hyperplasia of the liver in a case of myelofibrosis with extramedullary hematopoiesis and secondary portal venous hypertension. / Shorey, J.; Weinberg, M. N.; Frenkel, E. P.; Fallis, B. D.

In: American Journal of Clinical Pathology, Vol. 72, No. 1, 1979, p. 122-125.

Research output: Contribution to journalArticle

@article{bf76fa8602454c5fae7676cda1b98813,
title = "Nodular regenerative hyperplasia of the liver in a case of myelofibrosis with extramedullary hematopoiesis and secondary portal venous hypertension",
abstract = "Nodular regenerative hyperplasia of the liver was identified at autopsy in a patient with myelofibrosis with extramedullary hematopoiesis, an association not previously reported. Portal venous hypertension, documented during the patient's terminal hospitalization, was ascribed, in part, to a high rate of blood flow through the enlarged spleen. Possible mechanisms accounting for the development of nodular regenerative hyperplasia of the liver, and evidence provided by this case pertinent to these mechanisms, are discussed.",
author = "J. Shorey and Weinberg, {M. N.} and Frenkel, {E. P.} and Fallis, {B. D.}",
year = "1979",
language = "English (US)",
volume = "72",
pages = "122--125",
journal = "American Journal of Clinical Pathology",
issn = "0002-9173",
publisher = "American Society of Clinical Pathologists",
number = "1",

}

TY - JOUR

T1 - Nodular regenerative hyperplasia of the liver in a case of myelofibrosis with extramedullary hematopoiesis and secondary portal venous hypertension

AU - Shorey, J.

AU - Weinberg, M. N.

AU - Frenkel, E. P.

AU - Fallis, B. D.

PY - 1979

Y1 - 1979

N2 - Nodular regenerative hyperplasia of the liver was identified at autopsy in a patient with myelofibrosis with extramedullary hematopoiesis, an association not previously reported. Portal venous hypertension, documented during the patient's terminal hospitalization, was ascribed, in part, to a high rate of blood flow through the enlarged spleen. Possible mechanisms accounting for the development of nodular regenerative hyperplasia of the liver, and evidence provided by this case pertinent to these mechanisms, are discussed.

AB - Nodular regenerative hyperplasia of the liver was identified at autopsy in a patient with myelofibrosis with extramedullary hematopoiesis, an association not previously reported. Portal venous hypertension, documented during the patient's terminal hospitalization, was ascribed, in part, to a high rate of blood flow through the enlarged spleen. Possible mechanisms accounting for the development of nodular regenerative hyperplasia of the liver, and evidence provided by this case pertinent to these mechanisms, are discussed.

UR - http://www.scopus.com/inward/record.url?scp=0018762201&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018762201&partnerID=8YFLogxK

M3 - Article

VL - 72

SP - 122

EP - 125

JO - American Journal of Clinical Pathology

JF - American Journal of Clinical Pathology

SN - 0002-9173

IS - 1

ER -