Non-deprotonative primary and secondary amination of (hetero)arylmetals

Zhe Zhou, Zhiwei Ma, Nicole Erin Behnke, Hongyin Gao, László Kürti

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Herein we disclose a novel method for the facile transfer of primary (-NH2) and secondary amino groups (-NHR) to heteroaryl-as well as arylcuprates at low temperature without the need for precious metal catalysts, ligands, excess reagents, protecting and/or Erecting groups. This one-pot transformation allows unprecedented functional group tolerance and it is wellsuited for the amination of electron-rich, electron-deficient as well as structurally complex (hetero)arylmetals. In some of the cases, only catalytic amounts of a copper (l) salt is required.

Original languageEnglish (US)
Pages (from-to)115-118
Number of pages4
JournalJournal of the American Chemical Society
Volume139
Issue number1
DOIs
StatePublished - Jan 11 2017

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Amination
Electrons
Precious metals
Functional groups
Copper
Salts
Metals
Ligands
Catalysts
Temperature

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Non-deprotonative primary and secondary amination of (hetero)arylmetals. / Zhou, Zhe; Ma, Zhiwei; Behnke, Nicole Erin; Gao, Hongyin; Kürti, László.

In: Journal of the American Chemical Society, Vol. 139, No. 1, 11.01.2017, p. 115-118.

Research output: Contribution to journalArticle

Zhou, Zhe ; Ma, Zhiwei ; Behnke, Nicole Erin ; Gao, Hongyin ; Kürti, László. / Non-deprotonative primary and secondary amination of (hetero)arylmetals. In: Journal of the American Chemical Society. 2017 ; Vol. 139, No. 1. pp. 115-118.
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