Nontraditional Uses of US Contrast Agents in Abdominal Imaging and Intervention

Eric W. Pepin, Shaun M. Nordeck, David T. Fetzer

Research output: Contribution to journalArticlepeer-review


With the increasing availability of contrast-enhanced US (CEUS) worldwide and in the United States, the potential applications of this modality in abdominal imaging and intervention are continu-ing to expand. CEUS leverages the many inherent benefits of US with a safe and unique microbubble contrast agent.When injected intravenously, US contrast agents (UCAs) function as a pure blood pool agent, augmenting diagnostic US examinations such as vascular imaging. In the procedure suite, UCA can be used to improve needle visualization and depict active extravasation. UCA may also be injected through needles and tubes into various body spaces, al-lowing the assessment of the urinary system, indwelling catheters, and other tracts and cavities. Some venous and lymphatic lesions may be diagnosed with the direct injection of a UCA into these le-sions. The authors highlight some of the many applications that are relevant to the abdominal imaging professional and interventional radiologist but should not be considered a complete list, and users of UCAs should continue to consider uses beyond those tradition-ally highlighted in recent literature.

Original languageEnglish (US)
Pages (from-to)1724-1741
Number of pages18
Issue number6
StatePublished - 2022

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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