Ocular Side Effects Associated with Imatinib Mesylate and Perifosine for Gastrointestinal Stromal Tumor

S. Serdar Dogan, Bita Esmaeli

Research output: Contribution to journalReview article

20 Scopus citations

Abstract

Imatinib mesylate and perifosine are two relatively new drugs that have improved outcomes for patients with gastrointestinal stromal tumors in recent years. The ocular side effects of these two drugs are discussed in this chapter. The most common ocular side effect associated with imatinib mesylate is periorbital edema. Perifosine has been associated with a ring-shaped perilimbal corneal ulceration that can be treated with topical steroids and topical antibiotics.

Original languageEnglish (US)
Pages (from-to)109-114
Number of pages6
JournalHematology/Oncology Clinics of North America
Volume23
Issue number1
DOIs
StatePublished - Feb 1 2009
Externally publishedYes

Keywords

  • Gastrointestinal stromal tumor
  • Imatinib mesylate
  • Perifosine
  • Periorbital edema
  • Ulcerative keratitis

ASJC Scopus subject areas

  • Hematology
  • Oncology

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