Optimization of HDRBT boost dose delivery for patients with rectal cancer

Slobodan Devic, Hamed Bekerat, Aurelie Garant, Te Vuong

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose: We describe methods to improve dose delivery for patients with rectal cancer receiving boost brachytherapy after external beam radiotherapy. Methods and materials: Patients with rectal cancer who were ineligible or refusing surgery are treated with external beam radiotherapy and subsequently with three weekly image-guided volume-adapted high-dose-rate brachytherapy boosts of 10 Gy to the residual clinical target volume, for a total of 30 Gy in three fractions. Tungsten shielding placed at the center of intracavitary mold applicator and double-balloon technique was used to improve dose conformity to the target. Results: Our results show that the use of tungsten shield and double balloon reduces the dose gradient within the target volume to receive the prescription boost dose of 10 Gy from maximum dose of 60 Gy down to 20 Gy. Conclusions: We outlined two methods for achieving higher high-dose-rate brachytherapy dose conformity using the tungsten shielding rods (to spare contralateral healthy tissues) and double-balloon technique (to decrease dose gradient within the target to minimize dose to the proximal mucosa).

Original languageEnglish (US)
Pages (from-to)559-563
Number of pages5
JournalBrachytherapy
Volume18
Issue number4
DOIs
StatePublished - Jul 1 2019
Externally publishedYes

Fingerprint

Tungsten
Brachytherapy
Rectal Neoplasms
Radiotherapy
Prescriptions
Mucous Membrane
Fungi

Keywords

  • Boost
  • Dose optimization
  • Double-balloon
  • Health tissue spearing
  • Inoperable patients
  • Iridium-192
  • Multichannel applicator
  • Papillon legacy
  • Rectal cancer
  • Shielding

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

Cite this

Optimization of HDRBT boost dose delivery for patients with rectal cancer. / Devic, Slobodan; Bekerat, Hamed; Garant, Aurelie; Vuong, Te.

In: Brachytherapy, Vol. 18, No. 4, 01.07.2019, p. 559-563.

Research output: Contribution to journalArticle

Devic, Slobodan ; Bekerat, Hamed ; Garant, Aurelie ; Vuong, Te. / Optimization of HDRBT boost dose delivery for patients with rectal cancer. In: Brachytherapy. 2019 ; Vol. 18, No. 4. pp. 559-563.
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