Monosubstituted conjugated enynes smoothly underwent [4 + 2] homodimerization in the presence of palladium catalyst to give 4, α- and 2,6-disubstituted styrenes. Analogous cross-cycloaddition of conjugated enynes and diynes afforded a variety of polysubstituted benzenes, including phenol and aniline derivatives. Alkynes and diynes in the presence of a palladium catalyst underwent novel formal [2 + 2 + 2] sequential cyclotrimerization to afford multifunctional benzenes in one step with high degrees of regio- and chemoselectivities. Mechanisms of these novel transformations are discussed.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry
- Materials Chemistry