Paroxysmal cold hemoglobinuria and cardiopulmonary bypass

Alan P. Kypson; John J. Warner; Marilyn J. Telen; Carmelo A. Milano

doi:10.1016/S0003-4975(02)04337-0

Paroxysmal cold hemoglobinuria and cardiopulmonary bypass

Alan P. Kypson, John J. Warner, Marilyn J. Telen, Carmelo A. Milano

Internal Medicine

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Paroxysmal cold hemoglobinuria, a cold-reactive autoimmune disease associated with the Donath-Landsteiner antibody, has not been described in patients undergoing cardiac surgery. We report a case of mitral valve replacement in a woman with a positive Donath-Landsteiner antibody and a history of recurrent hemolysis and hemoglobinuria secondary to cold exposure. Successful perioperative management is described, as is a discussion of paroxysmal cold hemoglobinuria.

Original language	English (US)
Pages (from-to)	579-581
Number of pages	3
Journal	Annals of Thoracic Surgery
Volume	75
Issue number	2
DOIs	https://doi.org/10.1016/S0003-4975(02)04337-0
State	Published - Feb 1 2003

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

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abstract = "Paroxysmal cold hemoglobinuria, a cold-reactive autoimmune disease associated with the Donath-Landsteiner antibody, has not been described in patients undergoing cardiac surgery. We report a case of mitral valve replacement in a woman with a positive Donath-Landsteiner antibody and a history of recurrent hemolysis and hemoglobinuria secondary to cold exposure. Successful perioperative management is described, as is a discussion of paroxysmal cold hemoglobinuria.",

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AU - Kypson, Alan P.

AU - Warner, John J.

AU - Telen, Marilyn J.

AU - Milano, Carmelo A.

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N2 - Paroxysmal cold hemoglobinuria, a cold-reactive autoimmune disease associated with the Donath-Landsteiner antibody, has not been described in patients undergoing cardiac surgery. We report a case of mitral valve replacement in a woman with a positive Donath-Landsteiner antibody and a history of recurrent hemolysis and hemoglobinuria secondary to cold exposure. Successful perioperative management is described, as is a discussion of paroxysmal cold hemoglobinuria.

AB - Paroxysmal cold hemoglobinuria, a cold-reactive autoimmune disease associated with the Donath-Landsteiner antibody, has not been described in patients undergoing cardiac surgery. We report a case of mitral valve replacement in a woman with a positive Donath-Landsteiner antibody and a history of recurrent hemolysis and hemoglobinuria secondary to cold exposure. Successful perioperative management is described, as is a discussion of paroxysmal cold hemoglobinuria.

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Paroxysmal cold hemoglobinuria and cardiopulmonary bypass

Abstract

ASJC Scopus subject areas

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