Pathophysiology of 'cold spot' and 'hot spot' myocardial imaging agents used to detect ischemia or infarction

L. M. Buja; R. W. Parkey; F. J. Bonte; J. T. Willerson

Pathophysiology of 'cold spot' and 'hot spot' myocardial imaging agents used to detect ischemia or infarction

L. M. Buja, R. W. Parkey, F. J. Bonte, J. T. Willerson

Radiology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The purpose of this chapter is to summarize available information regarding the pathophysiological basis for the scintigraphic detection of ischemic and infarcted myocardium. Two general approaches have been developed: (1) negative ('cold spot') imaging with agents which concentrate in normal myocardium, and (2) positive ('hot spot') imaging with agents which concentrate in acutely infarcted myocardium. These two techniques for the detection of myocardial lesions are complimented by scintigraphic techniques which evaluate ventricular function and wall motion with agents which label the cardiac blood pool.

Original language	English (US)
Pages (from-to)	105-123
Number of pages	19
Journal	Cardiovascular Clinics
Volume	10
Issue number	2
State	Published - Dec 1 1979

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Cite this

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abstract = "The purpose of this chapter is to summarize available information regarding the pathophysiological basis for the scintigraphic detection of ischemic and infarcted myocardium. Two general approaches have been developed: (1) negative ('cold spot') imaging with agents which concentrate in normal myocardium, and (2) positive ('hot spot') imaging with agents which concentrate in acutely infarcted myocardium. These two techniques for the detection of myocardial lesions are complimented by scintigraphic techniques which evaluate ventricular function and wall motion with agents which label the cardiac blood pool.",

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AU - Parkey, R. W.

AU - Bonte, F. J.

AU - Willerson, J. T.

PY - 1979/12/1

Y1 - 1979/12/1

N2 - The purpose of this chapter is to summarize available information regarding the pathophysiological basis for the scintigraphic detection of ischemic and infarcted myocardium. Two general approaches have been developed: (1) negative ('cold spot') imaging with agents which concentrate in normal myocardium, and (2) positive ('hot spot') imaging with agents which concentrate in acutely infarcted myocardium. These two techniques for the detection of myocardial lesions are complimented by scintigraphic techniques which evaluate ventricular function and wall motion with agents which label the cardiac blood pool.

AB - The purpose of this chapter is to summarize available information regarding the pathophysiological basis for the scintigraphic detection of ischemic and infarcted myocardium. Two general approaches have been developed: (1) negative ('cold spot') imaging with agents which concentrate in normal myocardium, and (2) positive ('hot spot') imaging with agents which concentrate in acutely infarcted myocardium. These two techniques for the detection of myocardial lesions are complimented by scintigraphic techniques which evaluate ventricular function and wall motion with agents which label the cardiac blood pool.

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Pathophysiology of 'cold spot' and 'hot spot' myocardial imaging agents used to detect ischemia or infarction

Abstract

ASJC Scopus subject areas

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