Penetrating keratoplasty in acute herpetic corneal perforations

J. T. Patten, Harrison D Cavanagh, D. Pavan Langston

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Central corneal perforations have traditionally been managed by conjunctival flaps, tissue adhesives, soft contact lenses, corneal patches and other conservative measures for the immediate preservation of the eye. An alternative method of treatment is immediate penetrating keratoplasty. The results were presented of immediate keratoplasty in 25 eyes referred with acute central corneal perforations, 20 of herpetic origin and 5 with a chemical burn or dry eye syndrome. In all cases, the eye was successfully preserved. Twelve of 20 grafts (60%) for herpetic perforation went on to eventual clear grafts as opposed to 1 of 5 grafts (20%) in the dry eye or chemically burned patients. Significant complications encountered included cataract formation, secondary glaucoma and persistent epithelial defects; however, these should not preclude eventual restoration of good visual acuity. Penetrating keratoplasty in acutely inflamed and perforated eyes used to lead to angle closure and secondary glaucoma in a considerable number of cases, sometimes progressing to total disaster. It was shown that if enough corticosteroids are given immediately postoperatively, the risk for angle closure is not significant.

Original languageEnglish (US)
Pages (from-to)287-294
Number of pages8
JournalAnnals of Ophthalmology
Volume8
Issue number3
StatePublished - 1976

Fingerprint

Corneal Perforation
Penetrating Keratoplasty
Transplants
Dry Eye Syndromes
Chemical Burns
Tissue Adhesives
Capsule Opacification
Hydrophilic Contact Lens
Angle Closure Glaucoma
Corneal Transplantation
Disasters
Glaucoma
Visual Acuity
Adrenal Cortex Hormones

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Penetrating keratoplasty in acute herpetic corneal perforations. / Patten, J. T.; Cavanagh, Harrison D; Pavan Langston, D.

In: Annals of Ophthalmology, Vol. 8, No. 3, 1976, p. 287-294.

Research output: Contribution to journalArticle

Patten, JT, Cavanagh, HD & Pavan Langston, D 1976, 'Penetrating keratoplasty in acute herpetic corneal perforations', Annals of Ophthalmology, vol. 8, no. 3, pp. 287-294.
Patten, J. T. ; Cavanagh, Harrison D ; Pavan Langston, D. / Penetrating keratoplasty in acute herpetic corneal perforations. In: Annals of Ophthalmology. 1976 ; Vol. 8, No. 3. pp. 287-294.
@article{7206ba0240674dba94265afe81a28aed,
title = "Penetrating keratoplasty in acute herpetic corneal perforations",
abstract = "Central corneal perforations have traditionally been managed by conjunctival flaps, tissue adhesives, soft contact lenses, corneal patches and other conservative measures for the immediate preservation of the eye. An alternative method of treatment is immediate penetrating keratoplasty. The results were presented of immediate keratoplasty in 25 eyes referred with acute central corneal perforations, 20 of herpetic origin and 5 with a chemical burn or dry eye syndrome. In all cases, the eye was successfully preserved. Twelve of 20 grafts (60{\%}) for herpetic perforation went on to eventual clear grafts as opposed to 1 of 5 grafts (20{\%}) in the dry eye or chemically burned patients. Significant complications encountered included cataract formation, secondary glaucoma and persistent epithelial defects; however, these should not preclude eventual restoration of good visual acuity. Penetrating keratoplasty in acutely inflamed and perforated eyes used to lead to angle closure and secondary glaucoma in a considerable number of cases, sometimes progressing to total disaster. It was shown that if enough corticosteroids are given immediately postoperatively, the risk for angle closure is not significant.",
author = "Patten, {J. T.} and Cavanagh, {Harrison D} and {Pavan Langston}, D.",
year = "1976",
language = "English (US)",
volume = "8",
pages = "287--294",
journal = "Annals of Ophthalmology",
issn = "0003-4886",
publisher = "Humana Press",
number = "3",

}

TY - JOUR

T1 - Penetrating keratoplasty in acute herpetic corneal perforations

AU - Patten, J. T.

AU - Cavanagh, Harrison D

AU - Pavan Langston, D.

PY - 1976

Y1 - 1976

N2 - Central corneal perforations have traditionally been managed by conjunctival flaps, tissue adhesives, soft contact lenses, corneal patches and other conservative measures for the immediate preservation of the eye. An alternative method of treatment is immediate penetrating keratoplasty. The results were presented of immediate keratoplasty in 25 eyes referred with acute central corneal perforations, 20 of herpetic origin and 5 with a chemical burn or dry eye syndrome. In all cases, the eye was successfully preserved. Twelve of 20 grafts (60%) for herpetic perforation went on to eventual clear grafts as opposed to 1 of 5 grafts (20%) in the dry eye or chemically burned patients. Significant complications encountered included cataract formation, secondary glaucoma and persistent epithelial defects; however, these should not preclude eventual restoration of good visual acuity. Penetrating keratoplasty in acutely inflamed and perforated eyes used to lead to angle closure and secondary glaucoma in a considerable number of cases, sometimes progressing to total disaster. It was shown that if enough corticosteroids are given immediately postoperatively, the risk for angle closure is not significant.

AB - Central corneal perforations have traditionally been managed by conjunctival flaps, tissue adhesives, soft contact lenses, corneal patches and other conservative measures for the immediate preservation of the eye. An alternative method of treatment is immediate penetrating keratoplasty. The results were presented of immediate keratoplasty in 25 eyes referred with acute central corneal perforations, 20 of herpetic origin and 5 with a chemical burn or dry eye syndrome. In all cases, the eye was successfully preserved. Twelve of 20 grafts (60%) for herpetic perforation went on to eventual clear grafts as opposed to 1 of 5 grafts (20%) in the dry eye or chemically burned patients. Significant complications encountered included cataract formation, secondary glaucoma and persistent epithelial defects; however, these should not preclude eventual restoration of good visual acuity. Penetrating keratoplasty in acutely inflamed and perforated eyes used to lead to angle closure and secondary glaucoma in a considerable number of cases, sometimes progressing to total disaster. It was shown that if enough corticosteroids are given immediately postoperatively, the risk for angle closure is not significant.

UR - http://www.scopus.com/inward/record.url?scp=0017120990&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017120990&partnerID=8YFLogxK

M3 - Article

C2 - 773241

AN - SCOPUS:0017120990

VL - 8

SP - 287

EP - 294

JO - Annals of Ophthalmology

JF - Annals of Ophthalmology

SN - 0003-4886

IS - 3

ER -