TY - JOUR
T1 - Perinatal Factors Associated with Autism Spectrum Disorder in Jamaican Children
AU - Saroukhani, Sepideh
AU - Samms-Vaughan, Maureen
AU - Lee, Min Jae
AU - Bach, MacKinsey K.A.
AU - Bressler, Jan
AU - Hessabi, Manouchehr
AU - Grove, Megan L.
AU - Shakespeare-Pellington, Sydonnie
AU - Loveland, Katherine A.
AU - Rahbar, Mohammad H.
N1 - Publisher Copyright:
© 2019, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2020/9/1
Y1 - 2020/9/1
N2 - Mode of delivery, preterm birth, and low birth weight (LBW) are hypothesized to be associated with autism spectrum disorder (ASD) in the offspring. Using data from 343 ASD cases (2–8 years) and their age- and sex-matched typically developing controls in Jamaica we investigated these hypotheses. Our statistical analyses revealed that the parish of residence could modify the association between cesarean delivery and ASD, with a difference found in this relationship in Kingston parish [matched odds ratio (MOR) (95% confidence interval (CI)) 2.30 (1.17–4.53)] and other parishes [MOR (95% CI) 0.87 (0.48–1.59)]. Although the associations of LBW and preterm birth with ASD were not significant, we observed a significant interaction between LBW and the household socioeconomic status. These findings require replication.
AB - Mode of delivery, preterm birth, and low birth weight (LBW) are hypothesized to be associated with autism spectrum disorder (ASD) in the offspring. Using data from 343 ASD cases (2–8 years) and their age- and sex-matched typically developing controls in Jamaica we investigated these hypotheses. Our statistical analyses revealed that the parish of residence could modify the association between cesarean delivery and ASD, with a difference found in this relationship in Kingston parish [matched odds ratio (MOR) (95% confidence interval (CI)) 2.30 (1.17–4.53)] and other parishes [MOR (95% CI) 0.87 (0.48–1.59)]. Although the associations of LBW and preterm birth with ASD were not significant, we observed a significant interaction between LBW and the household socioeconomic status. These findings require replication.
KW - Autism spectrum disorder
KW - Cesarean delivery
KW - Jamaica
KW - Low birth weight
KW - Preterm birth
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U2 - 10.1007/s10803-019-04229-0
DO - 10.1007/s10803-019-04229-0
M3 - Article
C2 - 31538260
AN - SCOPUS:85073951856
SN - 0162-3257
VL - 50
SP - 3341
EP - 3357
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
IS - 9
ER -