Peripheral corneal disorders

Jeffrey B. Robin, David J. Schanzlin, Steven Verity, Bruce A. Barron, Robert C. Arffa, Enrique Suarez, Herbert E. Kaufman

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

The peripheral cornea is anatomically and physiologically distinct from its central counterpart. The major differences relate to the gradual transition of corneal tissues to those of the conjunctiva, episclera, and sclera; furthermore, the vascular structures, lymphatics, and inflammatory cells from these neighboring structures are intimately associated with the limbus and periphery of the cornea. The peripheral cornea is thereby predisposed to three main classes of disorders which do not normally involve the central cornea. First, local conditions affecting the sclera and conjunctiva may secondarily spread to involve the limbus and peripheral cornea. These include several infectious diseases, as well as hypersensitivity conditions, mass lesions, and degenerations. Second, due to the associated blood vessels and lymphatics, the peripheral cornea may be involved in a variety of systemic diseases, including vasculitides, autoimmune disorders, and abnormal metabolic conditions. Finally, there are several conditions, such as the noninflammatory peripheral degenerations, which primarily affect the peripheral cornea without associated ocular or systemic changes. In this review, we present a classification and discussion of the various disorders which may involve the peripheral cornea.

Original languageEnglish (US)
Pages (from-to)1-36
Number of pages36
JournalSurvey of Ophthalmology
Volume31
Issue number1
DOIs
StatePublished - 1986

Fingerprint

Cornea
Limbus Corneae
Sclera
Conjunctiva
Blood Vessels
Vasculitis
Communicable Diseases
Hypersensitivity

Keywords

  • collagen vascular diseases
  • corneal degenerations
  • corneal tumors
  • dellen
  • infectious keratitis
  • marginal ulcer
  • Mooren's ulcer
  • pellucid marginal degeneration
  • peripheral cornea
  • phlyctenulosis
  • rosacea
  • Terrien's marginal degeneration
  • vernal keratoconjunctivitis

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Robin, J. B., Schanzlin, D. J., Verity, S., Barron, B. A., Arffa, R. C., Suarez, E., & Kaufman, H. E. (1986). Peripheral corneal disorders. Survey of Ophthalmology, 31(1), 1-36. https://doi.org/10.1016/0039-6257(86)90049-4

Peripheral corneal disorders. / Robin, Jeffrey B.; Schanzlin, David J.; Verity, Steven; Barron, Bruce A.; Arffa, Robert C.; Suarez, Enrique; Kaufman, Herbert E.

In: Survey of Ophthalmology, Vol. 31, No. 1, 1986, p. 1-36.

Research output: Contribution to journalArticle

Robin, JB, Schanzlin, DJ, Verity, S, Barron, BA, Arffa, RC, Suarez, E & Kaufman, HE 1986, 'Peripheral corneal disorders', Survey of Ophthalmology, vol. 31, no. 1, pp. 1-36. https://doi.org/10.1016/0039-6257(86)90049-4
Robin JB, Schanzlin DJ, Verity S, Barron BA, Arffa RC, Suarez E et al. Peripheral corneal disorders. Survey of Ophthalmology. 1986;31(1):1-36. https://doi.org/10.1016/0039-6257(86)90049-4
Robin, Jeffrey B. ; Schanzlin, David J. ; Verity, Steven ; Barron, Bruce A. ; Arffa, Robert C. ; Suarez, Enrique ; Kaufman, Herbert E. / Peripheral corneal disorders. In: Survey of Ophthalmology. 1986 ; Vol. 31, No. 1. pp. 1-36.
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