Pharmacogenetics of anesthetic and analgesic agents

Stephen N. Palmer, N. Martin Giesecke, Simon C. Body, Stanton K. Shernan, Amanda A. Fox, Charles D. Collard

Research output: Contribution to journalArticlepeer-review

64 Scopus citations

Abstract

Predicting a patient's response to a particular drug has long been a goal of clinicians. Rapid advances in molecular biology have enabled researchers to identify associations between an individual's genetic profile and drug response. Pharmacogenetics is the study of the molecular mechanisms that underlie individual differences In drug metabolism, efficacy, and side effects. The pharmacogenetics of commonly used anesthetic and analgesic agents are reviewed.

Original languageEnglish (US)
Pages (from-to)663-671
Number of pages9
JournalAnesthesiology
Volume102
Issue number3
DOIs
StatePublished - Mar 2005

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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