Pharmacokinetics of potassium clavulanate in combination with amoxicillin in pediatric patients

J. D. Nelson, H. Kusmiesz, S. Shelton

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Two dosages of a liquid suspension formulation of amoxicillin and potassium clavulanate were tested in 34 infants and children. The smaller dosage resulted in suboptimal plasma concentrations. With the greater dosage (3.3 mg of clavulanate per kg and 13.3 mg of amoxicillin per kg), the mean peak plasma concentrations were 1.6 μg clavulanic acid per ml and 4.9 μg amoxicillin per ml.

Original languageEnglish (US)
Pages (from-to)681-682
Number of pages2
JournalAntimicrobial agents and chemotherapy
Volume21
Issue number4
DOIs
StatePublished - Jan 1 1982

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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