Ketones, alkyl and aryl halides, nitriles, and amides undergo reduction with lithium aluminium hydride in the solid LiAlH4-hydrocarbon two-phase system in the presence of typical phase-transfer catalysts (crown ethers and quaternary ammonium salts), the reaction being characterized by good yields; solubilization of lithium aluminium hydride in non-polar solvents is demonstrated.
|Original language||English (US)|
|Number of pages||2|
|Journal||Journal of the Chemical Society, Chemical Communications|
|Publication status||Published - Jan 1 1985|
ASJC Scopus subject areas
- Molecular Medicine