TY - JOUR
T1 - Photodynamic therapy for choroidal metastasis from carcinoid tumor
AU - Harbour, J. William
PY - 2004/6
Y1 - 2004/6
N2 - Purpose To determine the efficacy of photodynamic therapy for the treatment of a choroidal metastasis unresponsive to chemotherapy and radiation therapy. Design Interventional case report. Methods Photodynamic therapy with verteporfin was performed. Visual acuity, local tumor control, and complications were assessed. Results A 72-year-old woman was diagnosed with bilateral, biopsy-proven choroidal metastasis from a pulmonary carcinoid tumor that was resistant to chemotherapy and radiotherapy. The tumor in the left eye caused a retinal detachment and vision loss to light perception. The smaller lesion in the right eye progressively enlarged toward the fovea despite therapy and was treated with photodynamic therapy with verteporfin. Within 2 months, the exudative detachment resolved, the visual acuity returned to baseline, and the tumor volume decreased by 50%. Conclusion Photodynamic therapy may be an effective treatment option for selected patients with choroidal metastasis.
AB - Purpose To determine the efficacy of photodynamic therapy for the treatment of a choroidal metastasis unresponsive to chemotherapy and radiation therapy. Design Interventional case report. Methods Photodynamic therapy with verteporfin was performed. Visual acuity, local tumor control, and complications were assessed. Results A 72-year-old woman was diagnosed with bilateral, biopsy-proven choroidal metastasis from a pulmonary carcinoid tumor that was resistant to chemotherapy and radiotherapy. The tumor in the left eye caused a retinal detachment and vision loss to light perception. The smaller lesion in the right eye progressively enlarged toward the fovea despite therapy and was treated with photodynamic therapy with verteporfin. Within 2 months, the exudative detachment resolved, the visual acuity returned to baseline, and the tumor volume decreased by 50%. Conclusion Photodynamic therapy may be an effective treatment option for selected patients with choroidal metastasis.
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U2 - 10.1016/j.ajo.2004.01.009
DO - 10.1016/j.ajo.2004.01.009
M3 - Article
C2 - 15183811
AN - SCOPUS:2942616674
SN - 0002-9394
VL - 137
SP - 1143
EP - 1145
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 6
ER -