Plasmid DNA in Treponema pallidum (Nichols): Potential for antibiotic resistance by syphilis bacteria

Michael V. Norgard, James N. Miller

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

A plasmid DNA structure (approximate molecular weight = 7.5 × 10 6) was identified in the human pathogen Treponema pallidum (Nichols). The inability to isolate this plasmid from rabbit host tissue and the total lack of DNA homology of the plasmid with rabbit DNA has confirmed its Treponema pallidum origin. The observation documents a newly recognized and potentially significant genetic capability for Treponema pallidum.

Original languageEnglish (US)
Pages (from-to)553-555
Number of pages3
JournalScience
Volume213
Issue number4507
DOIs
StatePublished - 1981

ASJC Scopus subject areas

  • General

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