Polypharmacy in the HIV-infected older adult population

Lauren J. Gleason, Amneris E. Luque, Krupa Shah

Research output: Contribution to journalReview article

54 Scopus citations

Abstract

The prevalence of human immunodeficiency virus (HIV) infection among people older than 50 years is increasing. Older HIV-infected patients are particularly at risk for polypharmacy because they often have multiple comorbidities that require pharmacotherapy. Overall, there is not much known with respect to both the impact of aging on medication use in HIV-infected individuals, and the potential for interactions with highly active antiretroviral therapy (HAART) and coadministered medications and its clinical consequences. In this review, we aim to provide an overview of polypharmacy with a focus on its impact on the HIV-infected older adult population and to also provide some clinical considerations in this high-risk population.

Original languageEnglish (US)
Pages (from-to)749-763
Number of pages15
JournalClinical interventions in aging
Volume8
DOIs
StatePublished - Jun 20 2013

Keywords

  • HIV
  • Older adults
  • Polypharmacy

ASJC Scopus subject areas

  • Geriatrics and Gerontology

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