Presence of contractile-type smooth muscle cells in the endocardium

T. Suzuki, M. Aikawa, M. Kuro-o, M. Watanabe, K. Kimura, Y. Yazaki, R. Nagai

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A smooth muscle layer exists in the parietal endocardium. Notwithstanding previous pioneer work, little has been known on the phenotypes of these smooth muscles. In humans as in animals, smooth muscles show two distinct phenotypes, the 'synthetic' and 'contractile' states, which can be differentiated on the basis of the expression of two types of myosin heavy chain isoforms, SM1 and SM2. In this study, using SM1- and SM2-specific monoclonal antibodies, we performed immunohistochemical examinations to determine the phenotype of the endocardial smooth muscles. We report here that the endocardial smooth muscles have the contractile phenotype.

Original languageEnglish (US)
Pages (from-to)23-27
Number of pages5
JournalCardiology
Volume87
Issue number1
StatePublished - 1996

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Endocardium
Smooth Muscle Myocytes
Smooth Muscle
Phenotype
Myosin Heavy Chains
Protein Isoforms
Monoclonal Antibodies

Keywords

  • Contractile phenotype
  • Endocardium
  • Smooth muscle cells

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Suzuki, T., Aikawa, M., Kuro-o, M., Watanabe, M., Kimura, K., Yazaki, Y., & Nagai, R. (1996). Presence of contractile-type smooth muscle cells in the endocardium. Cardiology, 87(1), 23-27.

Presence of contractile-type smooth muscle cells in the endocardium. / Suzuki, T.; Aikawa, M.; Kuro-o, M.; Watanabe, M.; Kimura, K.; Yazaki, Y.; Nagai, R.

In: Cardiology, Vol. 87, No. 1, 1996, p. 23-27.

Research output: Contribution to journalArticle

Suzuki, T, Aikawa, M, Kuro-o, M, Watanabe, M, Kimura, K, Yazaki, Y & Nagai, R 1996, 'Presence of contractile-type smooth muscle cells in the endocardium', Cardiology, vol. 87, no. 1, pp. 23-27.
Suzuki T, Aikawa M, Kuro-o M, Watanabe M, Kimura K, Yazaki Y et al. Presence of contractile-type smooth muscle cells in the endocardium. Cardiology. 1996;87(1):23-27.
Suzuki, T. ; Aikawa, M. ; Kuro-o, M. ; Watanabe, M. ; Kimura, K. ; Yazaki, Y. ; Nagai, R. / Presence of contractile-type smooth muscle cells in the endocardium. In: Cardiology. 1996 ; Vol. 87, No. 1. pp. 23-27.
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