Primary gastric melanoma: Case report of a rare malignancy

Alexander Augustyn, Emma Diaz de Leon, Adam C. Yopp

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We report the case of a 64-year-old white male who presented to his primary care physician with complaints of fatigue. Physical exam was unremarkable and laboratory studies revealed profound anemia, for which the patient received a transfusion. Esophagoga - stro duodenoscopy revealed a bleeding mass in the proximal stomach that was histologically determined to be malignant melanoma, with immunohistochemical staining demonstrating positivity for SOX10, S100, MART-1, and HMG- 45. After an extensive dermatological exam no other primary lesion was identified. Whole body positron emission tomography (18-FDGPET/ CT) demonstrated pathologic uptake only in the area of the proximal stomach. For this reason, primary gastric melanoma was suspected in this patient. The patient underwent subtotal gastrectomy with mass excision followed by Roux-en-Y reconstruction. Very few cases of primary gastric melanoma have been reported. We report this case and present diagnostic criteria for primary non-cutaneous melanoma and discuss potential non-surgical therapies.

Original languageEnglish (US)
Article number5683
Pages (from-to)46-49
Number of pages4
JournalRare Tumors
Volume7
Issue number1
DOIs
StatePublished - 2015

Fingerprint

Melanoma
Stomach
Neoplasms
Duodenoscopy
Primary Care Physicians
Gastrectomy
Positron-Emission Tomography
Fatigue
Anemia
Staining and Labeling
Hemorrhage
Therapeutics

Keywords

  • Gastric
  • Gastrointestinal
  • Melanoma
  • Surgery

ASJC Scopus subject areas

  • Oncology
  • Histology

Cite this

Primary gastric melanoma : Case report of a rare malignancy. / Augustyn, Alexander; de Leon, Emma Diaz; Yopp, Adam C.

In: Rare Tumors, Vol. 7, No. 1, 5683, 2015, p. 46-49.

Research output: Contribution to journalArticle

Augustyn, Alexander ; de Leon, Emma Diaz ; Yopp, Adam C. / Primary gastric melanoma : Case report of a rare malignancy. In: Rare Tumors. 2015 ; Vol. 7, No. 1. pp. 46-49.
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