Procedural outcomes of revascularization of chronic total occlusion of native coronary arteries (from a multicenter United States registry)

Tesfaldet T. Michael, Dimitri Karmpaliotis, Emmanouil S. Brilakis, Eric Fuh, Vishal G. Patel, Owen Mogabgab, Mohammed Alomar, Ben L. Kirkland, Nicholas Lembo, Anna Kalynych, Harold Carlson, Subhash Banerjee, William Lombardi, David E. Kandzari

Research output: Contribution to journalArticle

80 Citations (Scopus)

Abstract

Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is a rapidly evolving area of interventional cardiology. We sought to examine the immediate procedural and in-hospital clinical outcomes of native coronary artery CTO PCI from a multicenter United States (US) registry. We retrospectively examined the procedural outcomes of 1,361 consecutive native coronary artery CTO PCIs performed at 3 US institutions from January 2006 to November 2011. Mean age was 65 ± 11 years, 85% of patients were men, 40% had diabetes, 37% had previous coronary artery bypass graft surgery, and 42% had previous PCI. The CTO target vessel was the right coronary artery (55%), circumflex (23%), left anterior descending artery (21%), and left main or bypass graft (1%). The retrograde approach was used in 34% of all procedures. The technical and procedural success rates were 85.5% and 84.2%, respectively. The mean procedural time, fluoroscopy time, and contrast utilization were 113 ± 61 minutes, 42 ± 29 minutes, and 294 ± 158 ml, respectively. In multivariate analysis, female gender, no previous coronary artery bypass surgery, and years since initiation of CTO PCI at each center were independent predictors of procedural success. Major complications occurred in 24 patients (1.8%). In conclusion, among selected US-based institutions with experienced operators, native coronary artery CTO PCI can be performed with high success and low major complication rates.

Original languageEnglish (US)
Pages (from-to)488-492
Number of pages5
JournalAmerican Journal of Cardiology
Volume112
Issue number4
DOIs
StatePublished - Aug 15 2013

Fingerprint

Percutaneous Coronary Intervention
Registries
Coronary Vessels
Coronary Artery Bypass
Transplants
Fluoroscopy
Cardiology
Multivariate Analysis
Arteries

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Procedural outcomes of revascularization of chronic total occlusion of native coronary arteries (from a multicenter United States registry). / Michael, Tesfaldet T.; Karmpaliotis, Dimitri; Brilakis, Emmanouil S.; Fuh, Eric; Patel, Vishal G.; Mogabgab, Owen; Alomar, Mohammed; Kirkland, Ben L.; Lembo, Nicholas; Kalynych, Anna; Carlson, Harold; Banerjee, Subhash; Lombardi, William; Kandzari, David E.

In: American Journal of Cardiology, Vol. 112, No. 4, 15.08.2013, p. 488-492.

Research output: Contribution to journalArticle

Michael, TT, Karmpaliotis, D, Brilakis, ES, Fuh, E, Patel, VG, Mogabgab, O, Alomar, M, Kirkland, BL, Lembo, N, Kalynych, A, Carlson, H, Banerjee, S, Lombardi, W & Kandzari, DE 2013, 'Procedural outcomes of revascularization of chronic total occlusion of native coronary arteries (from a multicenter United States registry)', American Journal of Cardiology, vol. 112, no. 4, pp. 488-492. https://doi.org/10.1016/j.amjcard.2013.04.008
Michael, Tesfaldet T. ; Karmpaliotis, Dimitri ; Brilakis, Emmanouil S. ; Fuh, Eric ; Patel, Vishal G. ; Mogabgab, Owen ; Alomar, Mohammed ; Kirkland, Ben L. ; Lembo, Nicholas ; Kalynych, Anna ; Carlson, Harold ; Banerjee, Subhash ; Lombardi, William ; Kandzari, David E. / Procedural outcomes of revascularization of chronic total occlusion of native coronary arteries (from a multicenter United States registry). In: American Journal of Cardiology. 2013 ; Vol. 112, No. 4. pp. 488-492.
@article{162d9964a0a8489b8b798156e6671781,
title = "Procedural outcomes of revascularization of chronic total occlusion of native coronary arteries (from a multicenter United States registry)",
abstract = "Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is a rapidly evolving area of interventional cardiology. We sought to examine the immediate procedural and in-hospital clinical outcomes of native coronary artery CTO PCI from a multicenter United States (US) registry. We retrospectively examined the procedural outcomes of 1,361 consecutive native coronary artery CTO PCIs performed at 3 US institutions from January 2006 to November 2011. Mean age was 65 ± 11 years, 85{\%} of patients were men, 40{\%} had diabetes, 37{\%} had previous coronary artery bypass graft surgery, and 42{\%} had previous PCI. The CTO target vessel was the right coronary artery (55{\%}), circumflex (23{\%}), left anterior descending artery (21{\%}), and left main or bypass graft (1{\%}). The retrograde approach was used in 34{\%} of all procedures. The technical and procedural success rates were 85.5{\%} and 84.2{\%}, respectively. The mean procedural time, fluoroscopy time, and contrast utilization were 113 ± 61 minutes, 42 ± 29 minutes, and 294 ± 158 ml, respectively. In multivariate analysis, female gender, no previous coronary artery bypass surgery, and years since initiation of CTO PCI at each center were independent predictors of procedural success. Major complications occurred in 24 patients (1.8{\%}). In conclusion, among selected US-based institutions with experienced operators, native coronary artery CTO PCI can be performed with high success and low major complication rates.",
author = "Michael, {Tesfaldet T.} and Dimitri Karmpaliotis and Brilakis, {Emmanouil S.} and Eric Fuh and Patel, {Vishal G.} and Owen Mogabgab and Mohammed Alomar and Kirkland, {Ben L.} and Nicholas Lembo and Anna Kalynych and Harold Carlson and Subhash Banerjee and William Lombardi and Kandzari, {David E.}",
year = "2013",
month = "8",
day = "15",
doi = "10.1016/j.amjcard.2013.04.008",
language = "English (US)",
volume = "112",
pages = "488--492",
journal = "American Journal of Cardiology",
issn = "0002-9149",
publisher = "Elsevier Inc.",
number = "4",

}

TY - JOUR

T1 - Procedural outcomes of revascularization of chronic total occlusion of native coronary arteries (from a multicenter United States registry)

AU - Michael, Tesfaldet T.

AU - Karmpaliotis, Dimitri

AU - Brilakis, Emmanouil S.

AU - Fuh, Eric

AU - Patel, Vishal G.

AU - Mogabgab, Owen

AU - Alomar, Mohammed

AU - Kirkland, Ben L.

AU - Lembo, Nicholas

AU - Kalynych, Anna

AU - Carlson, Harold

AU - Banerjee, Subhash

AU - Lombardi, William

AU - Kandzari, David E.

PY - 2013/8/15

Y1 - 2013/8/15

N2 - Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is a rapidly evolving area of interventional cardiology. We sought to examine the immediate procedural and in-hospital clinical outcomes of native coronary artery CTO PCI from a multicenter United States (US) registry. We retrospectively examined the procedural outcomes of 1,361 consecutive native coronary artery CTO PCIs performed at 3 US institutions from January 2006 to November 2011. Mean age was 65 ± 11 years, 85% of patients were men, 40% had diabetes, 37% had previous coronary artery bypass graft surgery, and 42% had previous PCI. The CTO target vessel was the right coronary artery (55%), circumflex (23%), left anterior descending artery (21%), and left main or bypass graft (1%). The retrograde approach was used in 34% of all procedures. The technical and procedural success rates were 85.5% and 84.2%, respectively. The mean procedural time, fluoroscopy time, and contrast utilization were 113 ± 61 minutes, 42 ± 29 minutes, and 294 ± 158 ml, respectively. In multivariate analysis, female gender, no previous coronary artery bypass surgery, and years since initiation of CTO PCI at each center were independent predictors of procedural success. Major complications occurred in 24 patients (1.8%). In conclusion, among selected US-based institutions with experienced operators, native coronary artery CTO PCI can be performed with high success and low major complication rates.

AB - Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is a rapidly evolving area of interventional cardiology. We sought to examine the immediate procedural and in-hospital clinical outcomes of native coronary artery CTO PCI from a multicenter United States (US) registry. We retrospectively examined the procedural outcomes of 1,361 consecutive native coronary artery CTO PCIs performed at 3 US institutions from January 2006 to November 2011. Mean age was 65 ± 11 years, 85% of patients were men, 40% had diabetes, 37% had previous coronary artery bypass graft surgery, and 42% had previous PCI. The CTO target vessel was the right coronary artery (55%), circumflex (23%), left anterior descending artery (21%), and left main or bypass graft (1%). The retrograde approach was used in 34% of all procedures. The technical and procedural success rates were 85.5% and 84.2%, respectively. The mean procedural time, fluoroscopy time, and contrast utilization were 113 ± 61 minutes, 42 ± 29 minutes, and 294 ± 158 ml, respectively. In multivariate analysis, female gender, no previous coronary artery bypass surgery, and years since initiation of CTO PCI at each center were independent predictors of procedural success. Major complications occurred in 24 patients (1.8%). In conclusion, among selected US-based institutions with experienced operators, native coronary artery CTO PCI can be performed with high success and low major complication rates.

UR - http://www.scopus.com/inward/record.url?scp=84881164079&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84881164079&partnerID=8YFLogxK

U2 - 10.1016/j.amjcard.2013.04.008

DO - 10.1016/j.amjcard.2013.04.008

M3 - Article

C2 - 23672987

AN - SCOPUS:84881164079

VL - 112

SP - 488

EP - 492

JO - American Journal of Cardiology

JF - American Journal of Cardiology

SN - 0002-9149

IS - 4

ER -